Results 41 to 50 of about 6,762 (204)
Genetic inactivation of β-catenin is salubrious whereas its activation is deleterious in desmoplakin cardiomyopathy [PDF]
, 2023 AIMS: Mutations in the DSP gene encoding desmoplakin, a constituent of the desmosomes at the intercalated discs (IDs), cause a phenotype that spans arrhythmogenic cardiomyopathy (ACM) and dilated cardiomyopathy.
Leila Rouhi +17 more
core +1 more source
Study of the desmoplakin protein using nuclear magnetic resonance spectroscopy and its interaction with gold nanoclusters using atomic force microscopy [PDF]
, 2014 Desmoplakin is a cytolinker protein vital to tissue exposed to shear forces, such as the skin and the heart. This thesis research combines three physical techniques for the study of desmoplakin, namely Nuclear Magnetic Resonance (NMR) Spectroscopy, Small
Rodriguez Zamora, Penelope
core +6 more sources
Development of antigen-specific ELISA for circulating autoantibodies to extracellular matrix protein 1 in lichen sclerosus [PDF]
, 2004 Lichen sclerosus is a common, acquired chronic inflammatory skin disease of unknown etiology, although circulating autoantibodies to the glycoprotein extracellular matrix protein 1 (ECM1) have been detected in most patients’ sera.
Sallie M. Neill +44 more
core +1 more source
Frontiers in Cell and Developmental Biology, 2022 Vimentin is a Type III intermediate filament (VIF) cytoskeletal protein that regulates the mechanical and migratory behavior of cells. Its expression is considered to be a marker for the epithelial to mesenchymal transition (EMT) that takes place in ...
Suganya Sivagurunathan +15 more
doaj +1 more source
, 2022 International audienceCell to cell interactions are crucial for morphogenesis and tissue formation. Desmoplakin (encoded by the Dsp gene) is a component of desmosomes and anchors the transmembrane adhesion proteins to the cytoskeleton.
Piprek, Rafal P +7 more
core +1 more source
Diagnostics, 2020 The present case report describes a mother and son with arrhythmogenic cardiomyopathy (ACM) with early and greater left ventricle (LV) involvement. The presence of curly hair in both, together with the resuscitated sudden cardiac death of the mother ...
Alina Elena Pătru +7 more
doaj +1 more source
Advanced Science, EarlyView.During pancreatitis, IL‐1α is released from necrotic acinar cells. In response to IL‐1α, pancreatic fibroblasts release chemokines and cytokines that regulate the recruitment of immune cells to the damaged organ. Furthermore, IL‐1α primes fibroblasts, resulting in increased tissue fibrosis during chronic pancreatitis.
Hala Mazloum +13 more
wiley +1 more source
Plasma desmoplakin I biomarker of vascular recurrence after ischemic stroke
, 2012 Stroke patients have a high risk of vascular recurrence. Biomarkers related to vascular recurrence, however, remain to be identified. The aim of the study was to identify, through proteomic analysis, plasma biomarkers associated with vascular recurrence ...
Tamargo Menéndez, Juan +8 more
core +1 more source
Frontiers in Genetics, 2022 Around one-third of patients diagnosed with idiopathic dilated cardiomyopathy (DCM) turn out to be familial cases, in only a few of which the identification of a pathogenic/likely pathogenic variant could be achieved. Cardiomyopathy caused by desmoplakin
Yi-Han Chang +11 more
doaj +1 more source
Desmoplakin Cardiomyopathy: Myocarditis-Like Episodes. [PDF]
CureusWe report a case of a 21-year-old woman who presented with recurrent chest pain over a three-year period, initially attributed to myocarditis. She first presented with elevated troponin levels and myocardial oedema on cardiac magnetic resonance imaging (MRI), consistent with acute myocarditis.
Fatrous T, Ibzea S, Zahir Hussain SH.
europepmc +3 more sources