Results 71 to 80 of about 10,499 (199)

Desmoplakin Maintains Transcellular Keratin Scaffolding and Protects From Intestinal InjurySummary

Cellular and Molecular Gastroenterology and Hepatology, 2022
Background & Aims: Desmosomes are intercellular junctions connecting keratin intermediate filaments of neighboring cells. The cadherins desmoglein 2 (Dsg2) and desmocollin 2 mediate cell–cell adhesion, whereas desmoplakin (Dsp) provides the ...
Annika Gross, Biaohuan Zhou, Lisa Bewersdorf, Nicole Schwarz, Gabriel M. Schacht, Peter Boor, Konrad Hoeft, Bernd Hoffmann, Elaine Fuchs, Rafael Kramann, Rudolf Merkel, Rudolf E. Leube, Pavel Strnad   +12 more
doaj   +1 more source

A molecular optomechanics approach reveals functional relevance of force transduction across talin and desmoplakin [PDF]

, 2023
Tanmay Sadhanasatish, Katharina Augustin, Lukas Windgasse, Anna Chrostek‐Grashoff, Matthias Rief, Carsten Grashoff   +5 more
openalex   +1 more source

Spatial Transcriptomic Assessments of Gene Expression Profiles in Human Peri‐Implant Lesions

Journal of Clinical Periodontology, Volume 53, Issue 1, Page 137-151, January 2026.
ABSTRACT Aim To analyse gene expression profiles in human tissue samples obtained from dental implant sites with or without peri‐implantitis. Materials and Methods Soft‐tissue biopsy samples obtained from patients presenting with implants with severe peri‐implantitis and adjacent reference implants with no signs of peri‐implantitis were analysed by ...
C. Dionigi, A. C. Ericson, A. Shikhan, L. Larsson, T. Berglundh   +4 more
wiley   +1 more source

Interleukin 1 Signaling Is Regulated by Leukemia Inhibitory Factor (LIF) and Is Aberrant in Lif−/− Mouse Uterus [PDF]

, 2008
This study addresses the regulation of the interleukin 1 (IL1) system in the murine uterine luminal epithelium (LE) and stroma by leukemia inhibitory factor (LIF). Using RT-PCR we compared expression of Il1a, Il1b, Il1rn, Il1r1, and Il1r2 during the pre-
Heath, John K
core  

Filamin C Truncation Mutations Are Associated With Arrhythmogenic Dilated Cardiomyopathy and Changes in the Cell-Cell Adhesion Structures. [PDF]

, 2018
OBJECTIVES: The purpose of this study was to assess the phenotype of Filamin C (FLNC) truncating variants in dilated cardiomyopathy (DCM) and understand the mechanism leading to an arrhythmogenic phenotype. BACKGROUND: Mutations in FLNC are known to lead
Abecasis, Asimaki, Asimaki, Asimaki, Begay, Brodehl, Campbell, Chelko, Daughenbaugh, Deo, Furst, Golbus, Gontier, Haas, Hershberger, Kley, Kley, Landrum, Lek, Liu, Marcus, Mestroni, Ortiz-Genga, Rowland, Spezzacatene, Valdes-Mas, van, Wang, Wu, Zhou   +29 more
core   +2 more sources

Association Between Single Nucleotide Polymorphisms and Disease Susceptibility, Survival, and Acute Exacerbation in Idiopathic Pulmonary Fibrosis

Respirology, Volume 31, Issue 1, Page 42-52, January 2026.
A polymorphism of DSP was associated with prognosis and acute exacerbation in Japanese individuals with idiopathic pulmonary fibrosis (IPF), and a polymorphism of TERT was associated with prognosis in the patients with IPF and acute exacerbation in those with unclassifiable idiopathic interstitial pneumonias, indicating the potential of personalised ...
Kazuya Tsubouchi, Toyoshi Yanagihara, Fumiaki Kiyomi, Yuzo Yamamoto, Masako Arimura‐Omori, Naoki Hamada, Katsuyuki Ichiki, Shohei Takata, Hiroshi Ishii, Yasuhiko Kitasato, Masaki Okamoto, Satoru Kawakami, Kazuhiro Yatera, Masayuki Kawasaki, Masaki Fujita, Shoji Tokunaga, Chikako Kiyohara, Yoichi Nakanishi, Isamu Okamoto   +18 more
wiley   +1 more source

FRAP analysis reveals stabilization of adhesion structures in the epidermis compared to cultured keratinocytes. [PDF]

PLoS ONE, 2013
Proper development and tissue maintenance requires cell-cell adhesion structures, which serve diverse and crucial roles in tissue morphogenesis. Epithelial tissues have three main types of cell-cell junctions: tight junctions, which play a major role in ...
Henry P Foote, Kaelyn D Sumigray, Terry Lechler   +2 more
doaj   +1 more source

Profound Re-Organization of Cell Surface Proteome in Equine Retinal Pigment Epithelial Cells in Response to In Vitro Culturing [PDF]

, 2012
The purpose of this study was to characterize the cell surface proteome of native compared to cultured equine retinal pigment epithelium (RPE) cells. The RPE plays an essential role in visual function and represents the outer blood-retinal barrier.
Aisenbrey, Alcazar, Alge, Bhutto, Bodaghi, Burke, Campochiaro, Christoph Szober, Chu, Claudia Alge-Priglinger, Clegg, Cornelia Deeg, Deeg, Deeg, Deeg, Deeg, Deeg, Degroote, Doherty, Dunn, Eberhardt, Ehrenhofer, Greer, Gullapalli, Gundersen, Ham, Hamel, Hauck, Hauck, Hauck, Hauck, Ho, Huang, Karl, Kerstin Euler, Kristina Fröhlich, Li, Limb, Machemer, Marius Ueffing, McBee, Milyushina, Mochizuki, Muramatsu, Nagai, Parker, Philp, Rizzolo, Rotilio, Singer, Stefanie Hauck, Strauss, Vacanti, Wolf, Wu   +54 more
core   +3 more sources

Inflammation and genetics in myo‐pericardial diseases: Insights from the Italian Study Group on Cardiomyopathies and Pericardial Diseases

ESC Heart Failure, Volume 12, Issue 6, Page 3987-3999, December 2025.
Proposed management of myo‐pericardial diseases. A systematic interdisciplinary approach to myo‐pericardial disease is essential to reach a correct diagnosis, starting from multiparametric characterization including EKG, echocardiography with GLS, laboratory exams and CMR or, in case of electric or haemodynamic instability, EMB.
Marco Merlo, Giulia Bassetto, Antonio Cannatà, Alberto Aimo, Camillo Autore, Barbara Bauce, Elena Biagini, Francesco Cappelli, Silvia Castelletti, Flavio D'Ascenzi, Cesare de Gregorio, Giuseppe Limongelli, Francesca Marzo, Beatrice Musumeci, Giacomo Tini, Roberto Pedrinelli, Pasquale Perrone Filardi, Gianfranco Sinagra, Massimo Imazio   +18 more
wiley   +1 more source

Serum-induced keratinization processes in an immortalized human meibomian gland epithelial cell line. [PDF]

PLoS ONE, 2015
The aim of this study was to evaluate a human meibomian gland epithelial cell line (HMGEC) as a model for meibomian gland (patho)physiology in vitro.HMGEC were cultured in the absence or presence of serum.
Ulrike Hampel, Antje Schröder, Todd Mitchell, Simon Brown, Peta Snikeris, Fabian Garreis, Carolina Kunnen, Mark Willcox, Friedrich Paulsen   +8 more
doaj   +1 more source