Results 41 to 50 of about 27,984 (242)

Tumor‐Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development

Advanced Science, EarlyView.
A single‐cell atlas of pancreatic ductal adenocarcinoma development reveals progressive ductal‐fibroblast‐immune crosstalk. Tumor‐derived LAMB3 drives the formation of immunosuppressive LRRC15+ fibroblasts through the ITGB1/FAK/MAPK/FOSL2 signaling. Glycolytic reprogramming upregulates LAMB3 and correlates with LRRC15+ fibroblast enrichment.
Xuqing Shi, Hangqi Liu, Jianru Sun, Xiaoding Liu, Xinping Jv, Longyun Chen, Yuhan Zhang, Hui Zhang, Xudong Xing, Ruiyu Li, Xinyi Ke, Jun Wang, Xianglin Yin, Bohan Liu, Qixian Liu, Yuan Wang, Junliang Lu, Shiyi Liu, Junyi Pang, Yumeng Cai, Menghua Dai, Fan Bai, Huanwen Wu, Zhiyong Liang   +23 more
wiley   +1 more source

Desmoplastic malignant melanoma on the buttock of an 18-year-old girl: Differentiation from desmoplastic nevus

, 1999
Melanocytic proliferation in young people may sometimes pose a diagnostic dilemma. This is particularly so when a desmoplastic component is present. Because the two main differential diagnoses, desmoplastic malignant melanoma and desmoplastic Spitz nevus,
Chan, GSW, Ng, WK, Choy, C, Chan, KW
core   +1 more source

Prevalence of Odontogenic Tumors in Udaipur Region -An Institutional Retrospective Analysis of 56 Cases

Journal of Pharmacy and Bioallied Sciences
Introduction: Odontogenic tumors are lesions that originate from the tooth-producing tissues or their remnants that remain entrapped either within the jawbones or into the adjacent soft tissues.
Satish Bhosale, Priyadarshini Kerur, Rohit Kumar, Pradeep Vishnoi, Rahul Chaplot, Gargi Nimbulkar   +5 more
doaj   +1 more source

The Dynamic Interaction between Extracellular Matrix Remodeling and Breast Tumor Progression

Cells, 2021
Desmoplastic tumors correspond to a unique tissue structure characterized by the abnormal deposition of extracellular matrix. Breast tumors are a typical example of this type of lesion, a property that allows its palpation and early detection.
Jorge Martinez, Patricio C. Smith
doaj   +1 more source

A 6-year-old boy with left temporal lobe mass. [PDF]

Brain Pathol
Brain Pathology, Volume 36, Issue 4, July 2026.
Liu K, Zhang S, Cao M, Huang R, Hu J, Shao H, Jin Y, Shen B, Zhou H, Sun L, Zhang X.   +10 more
europepmc   +2 more sources

Photodynamic Priming and Minocycline Overcome Chemoresistance by Reprogramming the Pancreatic Tumor Immune Microenvironment In Vivo

Advanced Science, EarlyView.
Dual priming with minocycline and photodynamic priming reprograms the pancreatic tumor microenvironment to overcome chemoresistance. By suppressing DNA repair enzyme Tdp1, inducing photooxidative damage, and enhancing irinotecan delivery via light‐activated nanoencapsulation, this strategy remodels the tumor microenvironment and drives immune ...
Fernanda V. Cabral, Jose Quilez‐Alburquerque, Olivia Mooradian, Shivendran Vytheswarran, Badri Parshad, Girgis Obaid, Huang‐Chiao Huang, Tayyaba Hasan   +7 more
wiley   +1 more source

Dynamic Self‐Clickable Decellularized Matrix Hydrogels for Regulating Vascularity and Enhancing Muscle Regeneration

Advanced Science, EarlyView.
Dynamic decellularized hydrogels are prepared using bovine decellularized small intestine submucosa (SIS) norbornene (dSIS‐NB). Bovine dSIS contained significant amounts of disulfide‐rich fibrillin‐I, enabling ‘self‐clickable’ thiol‐norbornene gelation and spatiotemporal tuning of hydrogel physicochemical properties.
Van Thuy Duong, Tuba Marjan, Ngoc Ha Luong, Taimoor H. Qazi, Chien‐Chi Lin   +4 more
wiley   +1 more source

The relationship between primary colorectal cancer histology and the histopathological growth patterns of corresponding liver metastases

BMC Cancer, 2022
Background The histopathological growth patterns (HGPs) are a prognostic and predictive biomarker in colorectal cancer liver metastasis (CRLM). This study evaluates the relationship between the HGP and primary colorectal cancer (CRC) histopathology ...
Diederik J. Höppener, Jean-Luc P. L. Stook, Boris Galjart, Pieter M. H. Nierop, Iris D. Nagtegaal, Peter B. Vermeulen, Dirk J. Grünhagen, Cornelis Verhoef, Michail Doukas, PALGA Group   +9 more
doaj   +1 more source

Cancer‐Associated Fibroblast‐Derived Sphingosine‐1‐Phosphate Activates a MALL–SDC4 Axis to Facilitate Perineural Invasion in Pancreatic Cancer

Advanced Science, EarlyView.
CAF‐derived S1P activates the S1PR3‐JNK‐Jun signaling pathway, thereby transcriptionally upregulating MALL expression in cancer cells. MALL increases the cell‐surface abundance of SDC4 by promoting its recycling and restricting its lysosomal degradation, which in turn enhances RhoA‐p‐MLC2‐dependent amoeboid invasion and SDC4‐PTN axis‐mediated cancer ...
Wang Peng, Mengdie Cao, Hai Huang, Shuya Bai, Luyao Liu, Jingwen Liang, Haochen Cui, Qiaodan Zhou, Shiru Chen, Jiamei Jiang, Luoxia Liu, Zhou Luan, Wei Chen, Si Xiong, Ronghua Wang, Bin Cheng, Yuchong Zhao   +16 more
wiley   +1 more source

Desmoplastic melanoma: Patterns of recurrence

, 1992
Desmoplastic melanoma is a rare type of malignant melanoma, recognized since 1971.
McLeod, G. Roderick, Smithers, B. Mark, Little, John H.   +2 more
core   +1 more source