Desmoplastic ameloblastoma in Indians: Report of five cases and review of literature
In the recent World Health Organization classification of odontogenic tumours, desmoplastic ameloblastoma has been characterized as a variant of ameloblastoma, with specific clinical, radiographical, and histological features.
Sivapathasundharam B +2 more
doaj
Multi-Cancer Computational Analysis Reveals Metastasis-Associated Variant of Desmoplastic Reaction Involving INHBA and THBS2 [PDF]
Despite extensive research, the details of the metastasis-associated biological mechanisms are largely unknown. Here, we analyze data from multiple cancers using a novel computational method identifying sets of genes whose coordinated overexpression ...
Vinay Varadan +3 more
core
Antiangiogenic immunotherapy suppresses desmoplastic and chemoresistant intestinal tumors in mice [PDF]
Mutations in APC promote colorectal cancer (CRC) progression through uncontrolled WNT signaling. Patients with desmoplastic CRC have a significantly worse prognosis and do not benefit from chemotherapy, but the mechanisms underlying the differential ...
Bianchi, R. +62 more
core +1 more source
The FGF/FGFR System in the Biology and Therapeutic Landscape of Pediatric CNS Tumors
ABSTRACT Central nervous system (CNS) tumors are the most common solid malignancies in children, comprising a highly heterogeneous group of neoplasms defined by distinct molecular alterations and clinical behaviors. Advances in molecular genetics have underscored the relevance of specific signaling pathways in driving pediatric tumorigenesis, among ...
Serena Filiberti +6 more
wiley +1 more source
Intra–Abdominal Desmoplastic Small Round Cell Tumor: A Rare Case Report and Review of Literature
Desmoplastic small round cell tumor (DSRCT) is a rare and aggressive type of sarcomatous tumor with a high proclivity ofmetastasis.While it predominantly affects the abdominal cavity, it is most often observed in younger males and histopathologically ...
Ankur Mudgal +3 more
doaj +1 more source
Purely Cystic Desmoplastic Ganglioglioma: An Incidental Finding in a Giant Cyst
Desmoplastic infantile ganglioglioma (DIG) is a rare supratentorial brain tumor occurring mostly before the age of 2 years. It has a good prognosis and total excision of the tumor is curative, necessitating no further treatment.
Sumit Bansal +3 more
doaj +1 more source
Intraoral desmoplastic fibroblastoma: A rare presentation
Desmoplastic fibroblastoma is an uncommon fibrous soft tissue tumor. Only a few cases have been reported in the literature till date. These slow growing, painless mass is most commonly seen in the upper extremities, but rarely in the head and neck region.
Santosh R Patil
core +1 more source
AI‐Driven Rational Design of Nanotherapeutics for Pancreatic Ductal Adenocarcinoma
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains a formidable malignancy characterized by late diagnosis, high recurrence rates, and pronounced chemoresistance. While nanoparticle‐based drug delivery systems (NDDS) offer theoretical advantages over conventional therapies, their clinical translation in PDAC has been severely limited.
Seohyun Choo +4 more
wiley +1 more source
Desmoplasia in Pancreatic Cancer. Can We Fight It?
The hallmark of pancreatic tumours, the desmoplastic reaction, provides a unique microenvironment that affects pancreatic tumour behaviour, its ability to grow and metastasize as well as resist the effects of chemotherapy.
E. E. Merika, K. N. Syrigos, M. W. Saif
doaj +1 more source
Impact of sleep insufficiency and recovery on cancer development
Abstract Sleep plays a critical role in overall health, and modern lifestyles, such as shift work and late‐night activities, can significantly impact sleep condition. Insufficient sleep has been associated with various adverse health outcomes, including an increased risk of tumor development.
Xiaxi Li, Chuanyuan Li, Yi Zhang
wiley +1 more source

