Biomarkers of inflammation in infants with cystic fibrosis
Background There are urgent needs for clinically relevant biomarkers to identify children with cystic fibrosis (CF) at risk for more progressive lung disease and to serve as outcome measures for clinical trials.
Theresa A. Laguna+6 more
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Extracellular Matrix of the Skin: 50 Years of Progress [PDF]
The extracellular connective tissue matrix of the skin is a complex aggregate of distinct collagenous and non-collagenous components. Optimal quantities and delicate interactions of these components are necessary to maintain normal physiologic properties
Fazio, Michael J+2 more
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Background Electronic cigarettes (e-cigs) were introduced as electronic nicotine delivery systems, and have become very popular in the USA and globally. There is a paucity of data on systemic injury biomarkers of vaping in e-cig users that can be used as
Kameshwar P. Singh+8 more
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MEASUREMENT OF DESMOSINE BY LIQUID CHROMATOGRAPHY–TANDEM MASS SPECTROMETRY AND ITS APPLICATION TO CHRONIC OBSTRUCTIVE PULMONARY DISEASE [PDF]
The mechanical properties of lung elastic fibers are derived from the specialized features of their core elastin protein, which contains distensible, coiled peptides that store the energy needed to expel air from the lungs.
Fagiola, Michael
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Copper-Heparin Inhalation Therapy To Repair Emphysema: A Scientific Rationale
Rob Janssen,1 Emiel FM Wouters,2 Wim Janssens,3 Willeke F Daamen,4 Paul Hagedoorn,5 Hugo AJM de Wit,6 Jef Serré,3 Ghislaine Gayan-Ramirez,3 Frits ME Franssen,2 Niki L Reynaert,2 Jan H von der Thüsen,7 Henderik W Frijlink5 1Department of ...
Janssen R+11 more
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Background The separation of emphysema from fibrosis is not as clear-cut as it was thought in early studies. These two pathologies may be present at the same time in human lungs and in mice either instilled with elastolytic enzymes or bleomycin or ...
Martorana Piero A+6 more
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Vitamin D receptor agonists increase klotho and osteopontin while decreasing aortic calcification in mice with chronic kidney disease fed a high phosphate diet [PDF]
Vascular calcification is common in chronic kidney disease, where cardiovascular mortality remains the leading cause of death. Patients with kidney disease are often prescribed vitamin D receptor agonists (VDRAs) that confer a survival benefit, but the ...
Giachelli, Cecilia M.+6 more
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Jerome Cantor,1 Shuren Ma,2 Gerard Turino2 1Department of Pharmaceutical Sciences, St John’s University, 2Department of Medicine, St Luke’s Mount Sinai Hospital Center, New York, NY, USA Abstract: A novel therapy for COPD ...
Cantor J, Ma S, Turino G
doaj
Understanding the molecular basis of the strength differences in skins used in leather manufacture : a dissertation presented in partial fulfillment of the requirements for the degree of Doctor of Philosophy at Massey University, Palmerston North, New Zealand [PDF]
Although skin structure and its physical properties have been extensively studied, little research has been devoted to understanding the links between them.
Naffa, Rafea Mustafa
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Optimisation of tennis string production from bovine intestine : a thesis presented in partial fulfilment of the requirements for the degree of Master in Technology at Massey University, Palmerston North, New Zealand [PDF]
The collagen and elastin content of the beef thread samples ranged from between 47-70% and 1.2-2.5% respectively. Amino acid analysis showed that the collagen present was probably collagen Type I while the non-collagenous proteins predominantly were ...
Komolwattanachai, Kanda
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