Matrice extracellulaire et vieillissement vasculaire [PDF]
, 2006 La matrice extracellulaire (MEC) est un assemblage de macromolécules (collagènes, protéoglycanes, élastine et glycoprotéines de structure) qui lient des cellules homologues ou hétérologues et les organisent en tissus.
Jacob, Marie-Paule
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Whole exome sequencing in patients with Williams-Beuren syndrome followed by disease modeling in mice points to four novel pathways that may modify stenosis risk [PDF]
, 2020 Supravalvular aortic stenosis (SVAS) is a narrowing of the aorta caused by elastin (ELN) haploinsufficiency. SVAS severity varies among patients with Williams-Beuren syndrome (WBS), a rare disorder that removes one copy of ELN and 25-27 other genes ...
Billington, Charles J +6 more
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Short-Term Second-Hand Smoke Exposure Predisposes the Lung to Inflammation, Elastic Fiber Injury, and Pulmonary Emphysema [PDF]
, 2021 To determine whether cigarette smoke exposure predisposes lungs to secondary injury, our laboratory developed a hamster model using lipopolysaccharide (LPS) to induce pulmonary inflammation following exposure to second-hand smoke.
Gu, George
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Opening the toolbox of alternative sampling strategies in clinical routine : a key-role for (LC-)MS/MS [PDF]
, 2016 A
Capiau, Sara +2 more
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The “History” of Desmosines: Forty Years of Debate on the Hypothesis That These Two Unnatural Amino Acids May Be Potential Biomarkers of Chronic Obstructive Pulmonary Disease [PDF]
, 2017 Desmosine and isodesmosine (collectively known as desmosines), two unnatural amino acids unique to mature elastin in humans, have been widely discussed as being potential biomarkers of disorders, which involve connective tissue and whose clinical ...
Cagnone, Maddalena +4 more
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Gender-dependent differences in plasma matrix metalloproteinase-8 elevated in pulmonary tuberculosis. [PDF]
, 2014 Tuberculosis (TB) remains a global health pandemic and greater understanding of underlying pathogenesis is required to develop novel therapeutic and diagnostic approaches.
Akul Singhania +51 more
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Elastin cross-linking in vitro. Studies on factors influencing the formation of desmosines by lysyl oxidase action on tropoelastin [PDF]
, 1978 A. Sampath Narayanan +3 more
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MEKC of desmosine and isodesmosine in urine of chronic destructive lung disease patients [PDF]
, 2000 Simona Viglio +14 more
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Liberation of desmosine and isodesmosine as amino acids from insoluble elastin by elastolytic proteases [PDF]
, 2011 Hideyuki Umeda +2 more
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