Results 41 to 50 of about 3,049 (232)
Enhancing Exosomal Delivery to Abdominal Aortic Aneurysms using Magnetically Responsive Chemotactic Nanomotors for Elastic Matrix Regenerative Repair. [PDF]
Adv Sci (Weinh)MMS/MSCE/CAT is a dual‐driven nanomotor, guided by magnetic fields to accumulate in low‐flow regions near arterial walls and subsequently targets abdominal aortic aneurysms (AAAs) via chemotaxis. This improves the delivery efficiency of mesenchymal stem cell exosomes and promotes elastic matrix regeneration repair, reversing AAA progression through ...
Wang L, Zhang Y, Mao C, Li X.
europepmc +2 more sources
Higher urine desmosine levels are associated with mortality in patients with acute lung injury [PDF]
American Journal of Physiology - Lung Cellular and Molecular Physiology, 2006 Dana McClintock +6 more
exaly +2 more sources
Desmosine, a biomarker for COPD: old and in the way [PDF]
European Respiratory Journal, 2012 In the assessment of clinical presentation and response to therapy in chronic obstructive pulmonary disease (COPD), there is a major need for the identification of suitable and reproducible parameters to evaluate disease progression and changes during interventional trials [1]; in other words, parameters (or markers) associated with clinical outcome ...
Maurizio Luisetti +2 more
openalex +6 more sources
Desmosine-Inspired Cross-Linkers for Hyaluronan Hydrogels [PDF]
Scientific Reports, 2013 We designed bioinspired cross-linkers based on desmosine, the cross-linker in natural elastin, to prepare hydrogels with thiolated hyaluronic acid. These short, rigid cross-linkers are based on pyridinium salts (as in desmosine) and can connect two polymer backbones.
Valentin Hagel +14 more
openalex +5 more sources
Urinary desmosine: A biomarker of structural lung injury during CF pulmonary exacerbation [PDF]
Pediatric Pulmonology, 2012 Theresa A Laguna +2 more
exaly +2 more sources
Total desmosines in plasma and urine correlate with lung function [PDF]
European Respiratory Journal, 2011 The aim of the present study was to evaluate the relationship between the matrix degradation biomarkers, desmosine and isodesmosine (desmosines), and lung function.Plasma and creatinine-corrected urinary total desmosines (P- and U-desmosines, respectively), lung function and diffusing capacity of the lung for carbon monoxide (DL,CO) were measured in a ...
Christoffer Lindberg +6 more
openalex +5 more sources
Fabrication of Insoluble Elastin by Enzyme‐Free Cross‐Linking
Macromolecular Bioscience, Volume 23, Issue 11, November 2023., 2023 A technique involving recombinant tropoelastin polymerization, coacervation, and allysine‐mediated cross‐linking with pyrroloquinoline quinone (PQQ) creates artificial elastin with native characteristics. PQQ, covalently attached to magnetic Sepharose beads, enables its repeated use in protein cross‐linking.
Tobias Hedtke +8 more
wiley +1 more source
Lysyl Oxidases as Targets for Cancer Therapy and Diagnostic Imaging
ChemMedChem, Volume 18, Issue 18, September 15, 2023., 2023 Over the past two decades, lysyl oxidases have been recognised as key enzymes in tumour invasion and metastasis, which has spurred efforts to develop inhibitors and molecular probes for therapeutic and imaging purposes, respectively. This review summarises the structural and functional aspects of these unique enzymes in relation to tumour progression ...
Reik Löser +7 more
wiley +1 more source