Results 51 to 60 of about 3,049 (232)

Clinical, histological, immunohistochemical, and biomolecular analysis of hyaluronic acid in early wound healing of human gingival tissues: A randomized, split‐mouth trial

Journal of Periodontology, Volume 94, Issue 7, Page 868-881, July 2023., 2023
Abstract Background Hyaluronic acid (HA) exerts a fundamental role in tissue repair. In vitro and animal studies demonstrated its ability to enhance wound healing. Nevertheless, in vivo human studies evaluating mechanisms involved in oral soft tissue repair are lacking.
Andrea Pilloni, Lorenzo Marini, Nicoletta Gagliano, Elena Canciani, Claudia Dellavia, Laura Brigida Cornaghi, Ezio Costa, Mariana A. Rojas   +7 more
wiley   +1 more source

Elastic fibers: formation, function, and fate during aging and disease

The FEBS Journal, Volume 289, Issue 13, Page 3704-3730, July 2022., 2022
Elastic fibers are vital extracellular components of vertebrates providing numerous tissues and organs with the elasticity and resilience required for their function. Here, we review the current knowledge and discuss open questions on the formation, structure, and functions of elastic fibers and how aging and diseases affect their fate over the human ...
Christian E. H. Schmelzer, Laurent Duca
wiley   +1 more source

The fibrillin microfibril/elastic fibre network: A critical extracellular supramolecular scaffold to balance skin homoeostasis

Experimental Dermatology, Volume 30, Issue 1, Page 25-37, January 2021., 2021
Abstract Supramolecular networks composed of fibrillins (fibrillin‐1 and fibrillin‐2) and associated ligands form intricate cellular microenvironments which balance skin homoeostasis and direct remodelling. Fibrillins assemble into microfibrils which are not only indispensable for conferring elasticity to the skin, but also control the bioavailability ...
Christin S. Adamo, Alexandra V. Zuk, Gerhard Sengle   +2 more
wiley   +1 more source

Isotope-dilution LC-MS/MS analysis of the elastin crosslinkers desmosine and isodesmosine in acute cerebral stroke patients

RSC Advances, 2021
Utilizing chemically synthesized an isotopically labeled internal standard, isodesmosine-13C3,15N1, an isotope-dilution LC-MS/MS method was established. Concentrations of desmosine and isodesmosine in plasma of acute cerebral stroke patients and healthy ...
Ayame Mikagi, Ryosuke Tashiro, Tomoo Inoue, Riki Anzawa, Akiho Imura, Takahiro Tanigawa, Tomohisa Ishida, Takashi Inoue, Kuniyasu Niizuma, T. Tominaga, Toyonobu Usuki   +10 more
semanticscholar   +1 more source

The elastin peptide VGVAPG increases CD4+ T-cell IL-4 production in patients with chronic obstructive pulmonary disease

Respiratory Research, 2021
Background In chronic obstructive pulmonary disease (COPD), lung-infiltrating inflammatory cells secrete proteases and participate in elastin breakdown and genesis of elastin-derived peptides (EP).
Flora Lemaire, Sandra Audonnet, Jeanne-Marie Perotin, Pierre Gaudry, Sandra Dury, Julien Ancel, François Lebargy, Frank Antonicelli, Gaëtan Deslée, Richard Le Naour   +9 more
doaj   +1 more source

Simultaneous Upregulation of Elastolytic and Elastogenic Factors Are Necessary for Regulated Collateral Diameter Expansion

Frontiers in Cardiovascular Medicine, 2022
Background: During arteriogenesis, outward remodeling of the arterial wall expands luminal diameter to produce increased conductance in developing collaterals. We have previously shown that diameter expansion without loss of internal elastic lamina (IEL)
Elizabeth Andraska, Nolan Skirtich, Dylan McCreary, Rohan Kulkarni, Edith Tzeng, Ryan McEnaney   +5 more
doaj   +1 more source

Elastin is Localised to the Interfascicular Matrix of Energy Storing Tendons and Becomes Increasingly Disorganised With Ageing [PDF]

, 2017
Tendon is composed of fascicles bound together by the interfascicular matrix (IFM). Energy storing tendons are more elastic and extensible than positional tendons; behaviour provided by specialisation of the IFM to enable repeated interfascicular sliding
A Heinz, AJ Viera, B Vrhovski, C Thorpe, C Thorpe, CT Thorpe, CT Thorpe, CT Thorpe, CT Thorpe, CT Thorpe, CT Thorpe, D Bedell-Hogan, EL Batson, F Ramirez, H Birch, H Oxlund, H Tempfer, HL Birch, IM Braverman, J Fallon, JA Foster, JA Foster, JA Pierce, JE Wagenseil, JF Innes, K Kubo, KD Smith, L Nimeskern, L Robert, L Robert, M Akagawa, M Benjamin, M Luisetti, MJ Sherratt, P Berens, P Kannus, PPY Lui, R Alexander, R Ker, SA Fenwick, SE Greenwald, SG Dakin, T Watanabe, TB Csóka, TC Lee, TM Grant, TM Grant, Z Gunja-Smith, Z Liu   +48 more
core   +3 more sources

Fibulin-4 is essential for maintaining arterial wall integrity in conduit but not muscular arteries [PDF]

, 2017
Homozygous or compound heterozygous mutations in fibulin-4 (FBLN4) lead to autosomal recessive cutis laxa type 1B (ARCL1B), a multisystem disorder characterized by significant cardiovascular abnormalities, including abnormal elastin assembly, arterial ...
Broekelmann, Thomas J, Chu, Mon-Li, Halabi, Carmen M, Lee, Vivian S, Lin, Michelle, Mecham, Robert P   +5 more
core   +3 more sources

Fingerprinting Desmosine-Containing Elastin Peptides [PDF]

Journal of the American Society for Mass Spectrometry, 2015
Elastin is a vital protein of the extracellular matrix of jawed vertebrates and provides elasticity to numerous tissues. It is secreted in the form of its soluble precursor tropoelastin, which is subsequently cross-linked in the course of the elastic fiber assembly.
Schräder, Christoph U, Heinz, Andrea, Majovsky, Petra, Schmelzer, Christian E H   +3 more
openaire   +4 more sources

Pathogenesis of chronic obstructive pulmonary disease [PDF]

, 2005
The current paradigm for the pathogenesis of chronic obstructive pulmonary disease is that chronic airflow limitation results from an abnormal inflammatory response to inhaled particles and gases in the lung. Airspace inflammation appears to be different
Macnee, W
core   +2 more sources