Results 51 to 60 of about 2,402 (209)

Oxidative Stress: A Possible Trigger for Pelvic Organ Prolapse

open access: yesJournal of Immunology Research, Volume 2020, Issue 1, 2020., 2020
Pelvic organ prolapse is a frequent health problem in women, encountered worldwide, its physiopathology being still incompletely understood. The integrity of the pelvic‐supportive structures is a key element that prevents the prolapse of the pelvic organs.
Radu Dragos Marcu   +9 more
wiley   +1 more source

Vitamin K2 (MK-7) attenuates LPS-induced acute lung injury via inhibiting inflammation, apoptosis, and ferroptosis.

open access: yesPLoS ONE, 2023
Acute lung injury (ALI) is a life-threatening disease that has received considerable critical attention in the field of intensive care. This study aimed to explore the role and mechanism of vitamin K2 (VK2) in ALI.
Yulian Wang   +7 more
doaj   +1 more source

Does urinary peptide content differ between COPD patients with and without inherited alpha-1 antitrypsin deficiency? [PDF]

open access: yes, 2017
Differentiating between chronic obstructive pulmonary disease (COPD) patients with normal (PiMM) or deficient (PiZZ) genetic variants of alpha-1 antitrypsin (A1AT) is important not only for understanding the pathobiology of disease progression but also ...
Carleo, Alfonso   +7 more
core   +2 more sources

Total desmosines in plasma and urine correlate with lung function [PDF]

open access: bronzeEuropean Respiratory Journal, 2011
The aim of the present study was to evaluate the relationship between the matrix degradation biomarkers, desmosine and isodesmosine (desmosines), and lung function.Plasma and creatinine-corrected urinary total desmosines (P- and U-desmosines, respectively), lung function and diffusing capacity of the lung for carbon monoxide (DL,CO) were measured in a ...
Christoffer Lindberg   +6 more
openalex   +4 more sources

IsoChichibabin desmosine-13C3,15N1 synthesis and quantitative LC-MS/MS analysis of desmosine and isodesmosine in human skin

open access: yesBioorganic & Medicinal Chemistry, 2021
Desmosine and isodesmosine are crosslinking amino acids of elastin, which is an essential component of the dermal extracellular matrix protein. Quantitative analysis of crosslinker desmosines in human skin dermis has not been fully achieved due to the insoluble nature of elastin protein.
Mika, Hirose   +6 more
openaire   +2 more sources

Neutrophil elastase activity is associated with exacerbations and lung function decline in Bronchiectasis [PDF]

open access: yes, 2017
Rationale: Sputum neutrophil elastase and serum desmosine, a linked marker of endogenous elastin degradation, are possible biomarkers of disease severity and progression in bronchiectasis.
Alison Dicker   +17 more
core   +2 more sources

Photolysis of Desmosine and Isodesmosine by Ultraviolet Light [PDF]

open access: yesEuropean Journal of Biochemistry, 1976
Desmosine and isodesmosine were separated by ion‐exchange and paper chromatography, after acid hydrolysis of purified elastin from beef ligamentum nuchae. The fractions obtained by ion‐exchange chromatography were clearly mixtures of related compounds.
R, Baurain, J F, Larochelle, F, Lamy
openaire   +2 more sources

Short-term variability of biomarkers of proteinase activity in patients with emphysema associated with type Z alpha-1-antitrypsin deficiency

open access: yesRespiratory Research, 2005
Background The burden of proteinases from inflammatory cells in the lung of subjects with type Pi ZZ of alpha-1-antitrypsin deficiency is higher than in those without the deficiency.
Nieuwenhuizen Willem   +8 more
doaj   +1 more source

Dose-Dependent Prevention of Fibrosis in Aorta of Salt-Loaded Stroke-Prone Spontaneously Hypertensive Rats by Combined Delapril and Indapamide treatment. [PDF]

open access: yes, 2002
Combined treatment with the angiotensin-converting enzyme (ACE) inhibitor delapril and the diuretic indapamide prevented vascular damage in vital organs of salt-loaded stroke-prone spontaneously hypertensive rats (SHRsp).
B., Bacchelli   +5 more
core   +1 more source

Assessment of some biochemical markers in electronic nicotine device smokers in Diyala province [PDF]

open access: yesPharmacia
Background: Vaping has gained significant popularity among young people in recent years as an alternative to conventional smoking. Despite being promoted as a safer substitute, the health consequences of vaping remain largely unknown. One area of concern
Omar D. Salman   +3 more
doaj   +3 more sources

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