Results 61 to 70 of about 2,402 (209)

Sterilization of lung matrices by supercritical carbon dioxide [PDF]

, 2016
Lung engineering is a potential alternative to transplantation for patients with end-stage pulmonary failure. Two challenges critical to the successful development of an engineered lung developed from a decellularized scaffold include (i) the suppression
Balestrini, Jenna L, Blatt, Kelly M S, Broekelmann, Tom J, Gard, Ashley L, Huie, Janet, Liu, Angela, Mecham, Robert P, Niklason, Laura E, Schwan, Jonas, Wilcox, Elise C, Zhao, Liping   +10 more
core   +2 more sources

Desmosine, a biomarker for COPD: old and in the way [PDF]

European Respiratory Journal, 2012
In the assessment of clinical presentation and response to therapy in chronic obstructive pulmonary disease (COPD), there is a major need for the identification of suitable and reproducible parameters to evaluate disease progression and changes during interventional trials [1]; in other words, parameters (or markers) associated with clinical outcome ...
Maurizio Luisetti, Jan Stolk, Paolo Iadarola   +2 more
openalex   +6 more sources

Preparation and Property Analyses of Elastin Peptides from Different Freshwater Fish Sources

Shipin gongye ke-ji
In order to fully utilize freshwater fish resources and develop new sources of elastin peptides, the basic information of the whole heart and bulbus arteriosus of three common bulk freshwater fish was measured in this study, including their mass, total ...
Shunfeng TIAN, Jing SHI, Shuping MA, Mengmeng FENG, Yongkang LUO, Yanfei JIANG, Chunyue ZHAO   +6 more
doaj   +1 more source

Increased circulating desmosine and age-dependent elastinolysis in idiopathic pulmonary fibrosis

Respiratory Research, 2018
Although chronic obstructive pulmonary disease (COPD) and idiopathic pulmonary fibrosis (IPF) seem to be opposite entities from a clinical perspective, common initial pathogenic steps have been suggested in both lung diseases.
Bart de Brouwer, Marjolein Drent, Jody M. W. van den Ouweland, Petal A. Wijnen, Coline H. M. van Moorsel, Otto Bekers, Jan C. Grutters, Eric S. White, Rob Janssen   +8 more
doaj   +1 more source

Confocal Raman microspectroscopy for spatially resolved tissue characterisation of disease‐linked spectra‐pathological signatures

Clinical and Translational Medicine, Volume 15, Issue 10, October 2025.
Confocal Raman microspectroscopy for spatially resolved tissue analysis: technology setup, spectra‐pathological signatures derived from computational methods, and tissue‐level insights for biomedical research and clinical applications. Abstract Raman spectroscopy is a versatile analytical technique for highly specific molecular characterisation of ...
Nektarios A. Valous, Inka Zörnig, Dirk Jäger   +2 more
wiley   +1 more source

Lysyl oxidase‐like 2 (LOXL2)‐mediated cross‐linking of tropoelastin

The FASEB Journal, Volume 33, Issue 4, Page 5468-5481, April 2019., 2019
ABSTRACTLysyl oxidases (LOXs) play a central role in extracellular matrix remodeling during development and tumor growth and fibrosis through cross‐linking of collagens and elastin. We have limited knowledge of the structure and substrate specificity of these secreted enzymes.
Christian E. H. Schmelzer, Andrea Heinz, Helen Troilo, Michael P. Lockhart‐Cairns, Thomas A. Jowitt, Marion F. Marchand, Laurent Bidault, Marine Bignon, Tobias Hedtke, Alain Barret, James C. McConnell, Michael J. Sherratt, Stéphane Germain, David J. S. Hulmes, Clair Baldock, Laurent Muller   +15 more
wiley   +1 more source

Measurement of MMP-9 and -12 degraded elastin (ELM) provides unique information on lung tissue degradation [PDF]

, 2012
BACKGROUND: Elastin is an essential component of selected connective tissues that provides a unique physiological elasticity. Elastin may be considered a signature protein of lungs where matrix metalloprotease (MMP) -9-and -12, may be considered the ...
Arkadiusz Nawrocki, Cory M Hogaboam, Diana J Leeming, Fernando J Martinez, Helene Skjøt-Arkil, Lloyd B Klickstein, Martin R Larsen, Meilan Han, Morten A Karsdal, Qinlong Zheng, Quoc Hai Trieu Nguyen, Rikke E Clausen, Yaguo Wang   +12 more
core   +1 more source

Vitamin K: Metabolism, Genetic Influences, and Chronic Disease Outcomes

Food Science &Nutrition, Volume 13, Issue 6, June 2025.
Vitamin K exists in two natural isoforms: phylloquinone (PK, vitamin K1) and menaquinones (MKs, vitamin K2), and is an essential cofactor for the post‐translational carboxylation of vitamin K‐dependent proteins (VKDPs). VKDPs are implicated in various physiological processes, including blood coagulation, calcium homeostasis, as well as metabolic and ...
Montana Dupuy, Nicola P. Bondonno, Pratik Pokharel, Allan Linneberg, Itamar Levinger, Carl Schultz, Jonathan M. Hodgson, Marc Sim   +7 more
wiley   +1 more source

The Possible Pathophysiological Outcomes and Mechanisms of Tourniquet‐Induced Ischemia‐Reperfusion Injury during Total Knee Arthroplasty

Oxidative Medicine and Cellular Longevity, Volume 2018, Issue 1, 2018., 2018
Ischemia and reperfusion (I/R) injury induced by tourniquet (TQ) application leads to the release of both oxygen free radicals and inflammatory cytokines. The skeletal muscle I/R may contribute to local skeletal muscle and remote organ damage affecting outcomes after total knee arthroplasty (TKA).
Prangmalee Leurcharusmee, Passakorn Sawaddiruk, Yodying Punjasawadwong, Nipon Chattipakorn, Siriporn C. Chattipakorn, Luciano Saso   +5 more
wiley   +1 more source

Matrice extracellulaire et vieillissement vasculaire [PDF]

, 2006
La matrice extracellulaire (MEC) est un assemblage de macromolécules (collagènes, protéoglycanes, élastine et glycoprotéines de structure) qui lient des cellules homologues ou hétérologues et les organisent en tissus.
Jacob, Marie-Paule
core   +1 more source