Results 101 to 110 of about 4,329 (200)
Vitamin D in plants: a review of occurrence, analysis, and biosynthesis. [PDF]
, 2013 The major function of vitamin D in vertebrates is maintenance of calcium homeostasis, but vitamin D insufficiency has also been linked to an increased risk of hypertension, autoimmune diseases, diabetes and cancer. Therefore, there is a growing awareness
Jakobsen, Jette, Jäpelt, Rie Bak
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Desmosterolosis and desmosterol homeostasis in the developing mouse brain
Journal of Inherited Metabolic Disease, 2019 AbstractCholesterol serves as a building material for cellular membranes and plays an important role in cellular metabolism. The brain relies on its own cholesterol biosynthesis, which starts during embryonic development. Cholesterol is synthesized from two immediate precursors, desmosterol and 7‐dehydrocholesterol (7‐DHC).
Luke B. Allen +4 more
openaire +3 more sources
Metabolomics of dietary fatty acid restriction in patients with phenylketonuria [PDF]
, 2012 Patients with phenylketonuria (PKU) have to follow a lifelong phenylalanine restricted diet. This type of diet markedly reduces the intake of saturated and unsaturated fatty acids especially long chain polyunsaturated fatty acids (LC-PUFA).
Berthold Koletzko +10 more
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Molecular actions of hypocholesterolaemic compounds from edible mushrooms [PDF]
, 2018 Cholesterol levels are strictly regulated to maintain its homeostasis; therefore, if it is not absorbed with the diet, the cholesterol biosynthetic pathway is enhanced and vice versa.
Gil-Ramírez, Alicia +2 more
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Profile of cholesterol-related sterols in aged amyloid precursor protein transgenic mouse brain
Journal of Lipid Research, 2002 Cholesterol is implicated to play a role in Alzheimer disease pathology. Therefore, the concentrations of cholesterol, its precursors, and its degradation products in brain homogenates of aging wild-type and β-amyloid precursor protein transgenic mice ...
Dieter Lütjohann +8 more
doaj +1 more source
GC-MS metabolomics reveals distinct profiles of low- and high-grade bladder cancer cultured cells [PDF]
, 2019 Previous studies have shown that metabolomics can be a useful tool to better understand the mechanisms of carcinogenesis; however, alterations in biochemical pathways that lead to bladder cancer (BC) development have hitherto not been fully investigated.
Araújo, Ana +7 more
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GC-MS-based endometabolome analysis differentiates prostate cancer from normal prostate cells [PDF]
, 2018 Prostate cancer (PCa) is an important health problem worldwide. Diagnosis and management of PCa is very complex because the detection of serum prostate specific antigen (PSA) has several drawbacks.
Araújo, Ana +7 more
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The influence of cholesterol precursor – desmosterol – on artificial lipid membranes
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2015 The disorders in cholesterol biosynthesis pathway and various diseases manifest in the accumulation of cholesterol precursors in the human tissues and cellular membranes. In this paper the effect of desmosterol--one of cholesterol precursors--on model lipid membranes was studied.
Hąc-Wydro, Katarzyna +4 more
openaire +3 more sources
Journal of Lipid Research, 1981 To test the hypothesis that high-responding rhesus monkeys should have a greater degree of feedback inhibition of hepatic cholesterol biosynthesis than the low-responding monkeys because the former group absorbs a higher percentage of cholesterol than ...
A K Bhattacharyya, D A Eggen
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Apollo gastrointestinal analysis [PDF]
Fecal bile acid patterns for the Apollo 17 flight were studied to determine the cause of diarrhea on the mission. The fecal sterol analysis gave no indication of an infectious diarrhea, or specific, or nonspecific etiology occurring during the entire ...
Huang, C. T. L., Nichols, B. L.
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