Results 1 to 10 of about 2,752 (167)

Synthetic estrogen and progestin effects on the myogenic program following damage in C2C12 murine myoblasts [PDF]

Physiological Reports
Females exhibit distinct responses to exercise‐induced muscle damage, possibly due to circulating hormone profiles. Despite the widespread use of oral contraceptives (OC) among females, the muscle damage and repair response during synthetic hormone use ...
Mai Wageh, Michael Kamal, Gianni Parise
doaj   +3 more sources

When CO2 sensing fails: Protective effects of sex hormones and potential mechanisms [PDF]

Journal of Neuroendocrinology, Volume 38, Issue 9, September 2026.
Abstract Breathing movements driven by the brainstem rhythmogenic neural networks rely on chemosensory inputs to produce a motor output that is homeostatically adjusted to the prevailing metabolic demand. The central CO2 chemoreflex is a critical component of respiratory neural circuitry, as defects in these sensors cause hypoventilation syndromes ...
Tara A. Janes, Silvia Cardani, Silvia Pagliardini   +2 more
wiley   +2 more sources

Efficacy and safety of desogestrel/ethinylestradiol 150/20 flexible extended regimen (FREEDOM 150/20) in dysmenorrhea: phase 3 study in Japan [PDF]

F&S Reports
Objective: To evaluate the efficacy and long-term safety of a user-driven flexible extended regimen of desogestrel 150 μg/ethinylestradiol 20 μg (DSG/EE 150/20) for the treatment of primary or secondary dysmenorrhea in women from Japan.
Kaori Koga, M.D., Ph.D., Daniela Colaci, M.D., MSc, Dr.PH., Madeline Grigg, M.D., Daisuke Goto, Ph.D., Tinghui Yu, Ph.D., Mikio Momoeda, M.D., Ph.D.   +5 more
doaj   +2 more sources

Sex Differences in the Effects of Etonogestrel on Respiratory Recovery in an In Vivo Rat Model of Central Chemoreflex Impairment [PDF]

Acta Physiologica, Volume 242, Issue 4, April 2026.
ABSTRACT Aim Rhythmic breathing movements driven by the brainstem rely on chemosensory inputs to homeostatically adjust motor output to the prevailing metabolic demand. The central CO2 chemoreflex is a critical component of this neural circuitry, as defects in these sensors cause hypoventilation syndromes, which are typically difficult to manage ...
Silvia Cardani, Tara A. Janes, Ryaad Asif, Silvia Pagliardini   +3 more
wiley   +2 more sources

Progestogen use and the risk of intracranial meningioma: a systematic review and meta-analysisResearch in context [PDF]

EClinicalMedicine
Summary: Background: Meningiomas are the most common primary brain tumours in adults. Concerns have emerged about a possible link between progestogen use and intracranial meningioma; we assessed this association.
Benoit Hudelist, Alexandre Roux, Emmanuelle Huet-Mignaton, Isabelle Dufaure-Gare, Alessandro Moiraghi, Angela Elia, Maimiti Seneca, Corentin Provost, Joseph Benzakoun, Alexandre Gehanno, Catherine Oppenheim, Marc Zanello, Johan Pallud   +12 more
doaj   +2 more sources

Prescription Medication Use During Pregnancy and Postpartum in Sweden 2007 to 2022 [PDF]

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 9, September 2026.
ABSTRACT Purpose Medication use during pregnancy has increased worldwide. The aim was to investigate patterns of prescription medication use during pregnancy and postpartum in Sweden 2007–2022. Methods We conducted a population‐based drug utilization study with linked data from the Swedish Medical Birth and Prescribed Drug Registers.
Essi Whaites Heinonen, Awad I. Smew, Silvia Segovia Chacón, Ulrika Nörby, Olof Stephansson, Anne K. Örtqvist, Cathrine Axfors, Pär Karlsson, Carolyn E. Cesta   +8 more
wiley   +2 more sources

Pharmacovigilance study of the association between progestogen and depression based on the FDA adverse event reporting System (FAERS) [PDF]

Scientific Reports
Progestogens commonly used in the clinic include levonorgestrel, etonogestrel, medroxyprogesterone, hydroxyprogesterone, progesterone, desogestrel, and megestrol.
Hui Gao, Xiaohan Zhai, Yan Hu, Hang Wu
doaj   +2 more sources

Considerations for Menstrual Suppression in Patients With Hematologic Malignancies [PDF]

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 3, March 2026.
ABSTRACT Patients who menstruate during treatment for hematologic malignancies have a higher risk of heavy vaginal bleeding due to thrombocytopenia caused by malignancy and myelosuppressive chemotherapy. Heavy menstrual bleeding is associated with significant morbidity in this patient population, and menstrual suppression is a standard of supportive ...
Sahaana Veeravalli, Allison Schepers, Lydia L. Benitez, Martina S. Fraga   +3 more
wiley   +2 more sources

Control of side effects in strategy for increasing adherence to combined oral contraceptives. The role for a three-phase desogestrel-containing drug

Акушерство, гинекология и репродукция, 2022
Introduction. The frequency of side effects when taking combined oral contraceptives (COCs) is still high, which is the reason for refusal to take COCs by women worldwide with a frequency of 30 to 81 %.
G. B. Dikke
doaj   +1 more source

Progesterone contraceptives: a place in practical gynecology (to practitioner aid) [PDF]

Гинекология, 2018
Progesterone-containing contraceptives do not have a significant impact on metabolic processes and can be prescribed to patients with systemic (diabetes mellitus, obesity) and other diseases. Desogestrel is a part of oral preparations in a dose of 75 mcg.
Y E Dobrokhotova, E I Borovkova, S A Zalesskaya   +2 more
doaj   +1 more source