Results 1 to 10 of about 24,069 (119)

Molecular classification of endometrial cancer in fertility-sparing-treatment: toward a personalized clinical approach [PDF]

Frontiers in Oncology
Molecular classification has emerged as a promising tool to improve patient selection and prognostic stratification in fertility sparing treatment (FST) for endometrial cancer (EC).
Filippo Alberto Ferrari, Giorgio Bogani, Matteo Pavone, Matteo Pavone, Matteo Pavone, Elena Olearo, Andrea Puppo, Marcello Ceccaroni   +7 more
doaj   +2 more sources

Pemberian Komunikasi Informasi Edukasi (KIE) Alat Kontrasepsi Pil Progestin di Era Pandemi Covid-19 Pada Ibu Post Partum di Praktik Mandiri Bidan (PMB) Kota Bengkulu

Dharma Raflesia, 2022
Post partum atau masa nifas adalah masa setelah keluarnya plasenta sampai alat-alat reproduksi pulih seperti sebelum hamil berlangsung 6 minggu. Pil progestin merupakan alat kontrasepsi yang aman untuk ibu post partum.
Dara Himalaya, Deni Maryani
doaj   +1 more source

Verteporfin reverses progestin resistance through YAP/TAZ-PI3K-Akt pathway in endometrial carcinoma

Cell Death Discovery, 2023
Progestin resistance is a problem for patients with endometrial carcinoma (EC) who require conservative treatment with progestin, and its underlying mechanisms remain unclear. YAP and TAZ (YAP/TAZ), downstream transcription coactivators of Hippo pathway,
Lina Wei, Xiaohong Ma, Yixin Hou, Tianyi Zhao, Rui Sun, Chunping Qiu, Yao Liu, Ziyi Qiu, Zhiming Liu, Jie Jiang   +9 more
doaj   +1 more source

Progestin plus metformin improves outcomes in patients with endometrial hyperplasia and early endometrial cancer more than progestin alone: a meta-analysis

Frontiers in Endocrinology, 2023
ObjectiveProgestin based therapy is the preferred option for fertility-sparing treatment of reproductive-age women with preserved fertility in endometrial hyperplasia (EH) or early endometrial cancer (EEC).
Fengping Shao, Yinguang Li, Yunhe Zhao
doaj   +1 more source

Germany Endometriosis Pattern Changes; Prevalence and Therapy over 2010 and 2019 Years: A Retrospective Cross Sectional Study [PDF]

International Journal of Fertility and Sterility, 2022
Background: The aim of this study was to investigate whether the prevalence and the therapy patterns of endometriosis differ in 2010 and 2019. Materials and Methods: This retrospective cross-sectional study was based on the data from the IQVIA Disease ...
Jacob Goehring, Maja Drewes, Matthias Kalder, Karel Kostev   +3 more
doaj   +1 more source

Vitamin D and Mitosis Evaluation in Endometriosis: A Step toward Discovering the Connection?

Biomedicines, 2023
(1) Background: The effects of serum vitamin D levels, the vitamin D receptor (VDR), and phosphohistone H3 (PHH3) in endometriosis were investigated in two cohorts of women with this pathology: those receiving hormonal treatment and those without ...
Daniela Roxana Matasariu, Cristina Elena Mandici, Alexandra Ursache, Alexandra Irma Gabriela Bausic, Iuliana Elena Bujor, Alexandra Elena Cristofor, Lucian Vasile Boiculese, Mihaela Grigore, Elvira Bratila, Ludmila Lozneanu   +9 more
doaj   +1 more source

Identification of potential models for predicting progestin insensitivity in patients with endometrial atypical hyperplasia and endometrioid endometrial cancer based on ATAC-Seq and RNA-Seq integrated analysis

Frontiers in Genetics, 2022
Objective: The aim of this study was to establish predictive models based on the molecular profiles of endometrial lesions, which might help identify progestin-insensitive endometrial atypical hyperplasia (EAH) or endometrioid endometrial cancer (EEC ...
Jia-Li Hu, Jia-Li Hu, Gulinazi Yierfulati, Gulinazi Yierfulati, Lu-Lu Wang, Lu-Lu Wang, Bing-Yi Yang, Bing-Yi Yang, Qiao-Ying Lv, Qiao-Ying Lv, Xiao-Jun Chen, Xiao-Jun Chen   +11 more
doaj   +1 more source

Effects of Etisterone and Contrasmine pills on clinical and biochemical findings of hyperandrogenism and metabolic parameters of patients with polycystic ovary syndrome: A randomized clinical trial [PDF]

Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2020
Introduction: Nowadays, selection of a contraceptive with most anti-androgenic effects is an important challenge in treatment of patients with polycystic ovary syndrome (PCOS).
Mina Amiri, Razieh Bidhendi-Yarandi, Fatemeh Nahidi, Fahimeh Ramezani Tehrani   +3 more
doaj   +1 more source

RNA‐seq and ATAC‐seq analysis of CD163+ macrophage‐induced progestin‐insensitive endometrial cancer cells

Cancer Medicine, 2023
Background Progestins are used as fertility‐sparing regimens for young patients with stage 1A endometrioid endometrial cancer (EEC) and atypical endometrial hyperplasia (AEH).
Lulu Wang, Qiaoying Lv, Pengfei Wu, Shuhan Luo, Sijia Liu, Xiaojun Chen, Xuezhen Luo   +6 more
doaj   +1 more source

Neurohypophysial and paracrine vasopressinergic signaling regulates aquaporin trafficking to hydrate marine teleost oocytes

Frontiers in Endocrinology, 2023
The dual aquaporin (Aqp1ab1/Aqp1ab2)-mediated hydration of marine teleost eggs, which occurs during oocyte meiosis resumption (maturation), is considered a key adaptation underpinning their evolutionary success in the oceans.
Alba Ferré, François Chauvigné, Magdalena Gozdowska, Ewa Kulczykowska, Roderick Nigel Finn, Roderick Nigel Finn, Joan Cerdà   +6 more
doaj   +1 more source