Results 91 to 100 of about 34,779 (287)
A Gut‐Brain Axis Underlying Succinate‐Associated Compulsive‐Like Behavior
Advanced Science, EarlyView.Gut‐derived succinate is associated with an excitatory‐inhibitory imbalance in dmPFC glutamatergic neurons, involving microglial SUCNR1 activation and vagal afferent signaling via upregulated gut 5‐HT4 receptors along the DVC‐CeA‐dmPFC circuit, changes that are linked to excessive compulsive‐like behavior.
Yi Li +12 more
wiley +1 more source
Higher Desolvation Energy Reduces Molecular Recognition in Multi-Drug Resistant HIV-1 Protease
Biology, 2012 Designing HIV-1 protease inhibitors that overcome drug-resistance is still a challenging task. In this study, four clinical isolates of multi-drug resistant HIV-1 proteases that exhibit resistance to all the US FDA-approved HIV-1 protease inhibitors and ...
Ladislau C. Kovari +6 more
doaj +1 more source
Rapid Context-Dependent Ligand Desolvation in Molecular Docking
, 2016 In structure-based screens for new ligands, a molecular docking algorithm must rapidly score many molecules in multiple configurations, accounting for both the ligand’s interactions with receptor and its competing interactions with solvent.
Brian K. Shoichet (434829) +1 more
core +1 more source
Advanced Science, EarlyView.A dual‐network hydrogel was prepared via a one‐pot method, incorporating vermiculite nanosheets as an additive. The negatively charged vermiculite nanosheets not only coordinate with zinc ions to facilitate Zn plating/stripping and suppress Zn dendrite growth, but also adsorb polyiodides to inhibit the shuttle effect, which significantly improves the ...
Yunlong Zhou +7 more
wiley +1 more source
, 2023 Supercapacitors have many applications in new energy and other high-tech fields. The desolvation effect on ions affects the capacity size of supercapacitors, and there are few relevant studies published in this field at present.
Shuwei Tang +4 more
core +1 more source
Advanced Science, EarlyView.This review elucidates the catalytic mechanisms of single‐atom catalysts (SACs) in accelerating lithium polysulfides redox kinetics. Subsequently, the modifications brought by asymmetric coordination chemistry and dual‐atom coordination structures in terms of geometric configuration engineering, molecular orbital hybridization, and interfacial charge ...
Peng Chen +7 more
wiley +1 more source
Aqueous vs. nonaqueous Zn-ion batteries: consequences of the desolvation penalty at the interface
, 2018 Comparison of intercalation of Zn2+ in layered V3O7·H2O in non-aqueous and aqueous electrolytes reveals a much higher desolvation penalty at the non-aqueous interface, a major factor in dictating the kinetics.
Brian Adams +5 more
core +1 more source
Triple‐Coupling Regulation Enables Dendrite‐Free Subzero Aqueous Zn‐Ion Batteries
Advanced Science, EarlyView.A formamide‐ethanol deep eutectic electrolyte enables triple‐coupling regulation of solvation structure, interfacial chemistry, and crystallographic Zn deposition. The reconstructed Zn2+ solvation reduces water activity and suppresses side reactions, while a robust hybrid SEI stabilizes the interface.
Mengyang Dong +8 more
wiley +1 more source
Advanced Science, EarlyView.We develop bio‐based, star‐branched polyamides from itaconic acid and cadaverine with tunable lower critical solution temperature (LCST) transitions for dynamic solar modulation. Specific metal ion coordination with pyrrolidone moieties drives precise phase transitions via calcium‐induced salting‐in and sodium‐induced salting‐out mechanisms. Formulated
Jie Liu +6 more
wiley +1 more source
, 2022 Many compounds take up solvent molecules into their structures during synthesis or storage, often resulting in new crystal structures with different physicochemical properties.
Armin Schulz +10 more
core