Results 121 to 130 of about 31,617 (291)

QRICH1 Disrupts Endoplasmic Reticulum Homeostasis and Amplifies NF‐κB Signaling in Periodontal Ligament Stem Cells to Exacerbate Diabetic Periodontitis

Advanced Science, EarlyView.
QRICH1 has been established as a key factor contributing to impaired osteogenic potential and accelerated apoptosis of PDLSCs in diabetic periodontitis. QRICH1 not only significantly enhances UPR‐associated apoptotic signaling but also amplifies NF‐κB‐mediated inflammatory responses. Its inhibition restores osteogenic capacity and reduces alveolar bone
Han Li, Xiaoyu Yang, He Wang, Yunchun Kuang, Yiyao Hu, Houxuan Li, Shuhong Li, Deping Zeng, Jie Li, Jinlin Song   +9 more
wiley   +1 more source

Effect of sodium chloride on monoclonal antibody desolvation particle size. [PDF]

(a) Schematic illustration of the monoclonal antibody (mAb) desolvation process in which 1.1 mL of acetonitrile was drop-wise added (0.5 mL/min) to 200 μL of mAb (10 mg/mL) at 20°C under stirring (1300 rpm).
Levi Collin Nelemans (16620807), Edwin Bremer (416900), Vinicio Alejandro Melo (6831323), Matej Buzgo (2095387), Aiva Simaite (1530016)   +4 more
core   +1 more source

Preparation of sodium alginate nanoparticles by desolvation technique using iso propyl alcohol as desolvating agent

International Journal of Biomedical and Advance Research, 2015
Objective : The present study was undertaken to prepare and characterize drug loaded Sodium Alginate nanoparticles using Desolvation technique. The model drug chosen was Ibuprofen. Method : These nanoparticles were prepared by two methods i.e; Continuous addition method and intermittent addition methods in which the addition of desolvating agent was ...
Krishna sailaja, Abbaraju, P., Swathi
openaire   +1 more source

Overcoming Interfacial Hurdles in Solid‐State Aluminum Batteries for Safe and Energy‐Dense Storage

Advanced Science, EarlyView.
Solid‐state aluminum batteries (SSABs) promise high energy density and intrinsic safety but face severe solid–solid interfacial challenges. This review reveals the three core hurdles—anode passivation, cathode contact loss, and electrolyte grain boundary resistance and discusses strategies including artificial interphases, alloying, and composite ...
Yunlei Wang, Xiaogang Zhang, Mingguang Wang, Yifan Wu, Shitao Dou, Taibin Wu   +5 more
wiley   +1 more source

Assisted Desolvation as a Key Kinetic Step for Crystal Growth [PDF]

, 2006
The crystallization of materials from a supersaturated solution is a fundamental chemical process.Although several very successful models that provide a qualitative understanding of the crystal growth process exist, in most cases the atomistic detail of ...
Gale, Julian, Piana, Stefano, Jones, Franca   +2 more
core  

Superior High‐Rate Ni‐Rich Lithium Batteries Based on Fast Ion‐Desolvation and Stable Solid‐Electrolyte Interphase

Advanced Science
The fast charging‐discharging performance of power batteries has very practical significance. In terms of electrochemistry, this requires fast and stable kinetics for electrochemical reaction processes.
Zhenxue Xiao, Siyuan Wu, Xiaozhe Ren, Minfei Fei, Shuai Hao, Xueping Gao, Guoran Li   +6 more
doaj   +1 more source

Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance

Advanced Science, EarlyView.
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer, Ian de Ridder, Mahjoobeh Ehsani, Marasim Khan, Justin Kale, Lukas P. Frenzel, David Andrews, Spyridoula Karamanou, Ana J. Garcia‐Saez, Geert Bultynck   +9 more
wiley   +1 more source

In Situ Alkali Metal Exfoliation‐Coupled Dilute CO2 Electrolysis to Synthesize Interlayer‐Expanded Graphite for High‐Rate Lithium Storage

Advanced Science, EarlyView.
Converting CO2 into advanced carbon materials capable of meeting the rapid lithium storage demands of lithium‐ion batteries creates a mutually beneficial scenario for both energy and environmental sectors. Here, we propose a stepwise CO2 electrolysis approach to transform dilute CO2 into interlayer‐expanded graphite using molten salt electrolyzers ...
Hao Zha, Xiaodan Zhang, Xinyu Li, Jiajun Li, Yuxin Wu, Xiaoyang Wang, Huayi Yin, Dihua Wang, Bowen Deng   +8 more
wiley   +1 more source

Probing the Stability of a β-Hairpin Scaffold after Desolvation

The Journal of Physical Chemistry Letters
The Journal of Physical Chemistry Letters, 15 (19)
Lukas R. Benzenberg, Paul Katzberger, Ri Wu, Jonas B. Metternich, Sereina Riniker, Renato Zenobi   +5 more
openaire   +3 more sources

Long‐Chain Molecule Reconstruction of Novel Solvation Structure to Stabilize Zinc Metal Anode

Advanced Science, EarlyView.
Triethylene glycol diacetate (TGD), with unique long‐chain characteristics and rich oxygen‐containing functional groups, was used as an electrolyte additive to reconstruct the solvation structure. TGD can reduce the erosion of H2O molecules on the Zn anode, effectively homogenize the electric field distribution. Therefore, the Zn//Zn symmetric cell can
Changdong Chen, Lingwei Xue, Gaojie Li, Xueli Chen, Yongjun Han, Liwei Mi, Yuqing Chen   +6 more
wiley   +1 more source