Results 191 to 200 of about 16,991 (224)

Chemical Imaging with Desorption Electrospray Ionization Mass Spectrometry

2010
Desorption electrospray ionization mass spectrometry (DESI-MS) is a relatively new ambient surface analysis method. This technique requires little or no sample preparation prior to the actual analysis. Along with other application areas, DESI-MS is used to obtain chemical images of different biomolecules in biological tissue sections.
Vilmos, Kertesz, Gary J, Van Berkel
openaire   +2 more sources

Droplet Dynamics and Ionization Mechanisms in Desorption Electrospray Ionization Mass Spectrometry

Analytical Chemistry, 2006
A droplet pickup and other mechanisms have been suggested for the ionization of biomolecules like peptides and proteins by desorption electrospray ionization. To verify this hypothesis phase Doppler particle analysis was used to study the sizes and velocities of droplets involved in DESI.
Andre, Venter, Paul E, Sojka, R Graham, Cooks   +2 more
openaire   +2 more sources

Characterization of polyethylenimine by electrospray ionization and matrix‐assisted laser desorption/ionization

Journal of Mass Spectrometry, 2011
Branched polyethylenimines (PEIs) with lower average molecular weights (600, 1200 and 1800 Da) have been studied by Electrospray Ionization (ESI) and Matrix‐Assisted Laser Desorption/Ionization (MALDI) mass spectrometry. In both, ESI and MALDI mass spectra, the main distribution arises from protonated PEI oligomers with NH2 end groups, [PEI + H ...
Edgardo, Rivera-Tirado, Chrys, Wesdemiotis   +1 more
openaire   +2 more sources

Delayed Desorption Improves Protein Analysis by Desorption Electrospray Ionization Mass Spectrometry

Journal of the American Society for Mass Spectrometry, 2020
Protein analysis by desorption electrospray ionization mass spectrometry (DESI-MS) is limited and often accompanied by a mass-dependent loss in sensitivity as protein molecular weight increases. Previously, incomplete dissolution was identified as a potential contributing factor to this limitation for larger proteins.
Tara L. Maser, Elahe Honarvar, Andre R. Venter   +2 more
openaire   +2 more sources

Effects of matrix, electrospray solution, and laser light on the desorption and ionization mechanisms in electrospray-assisted laser desorption ionization mass spectrometry

The Analyst, 2010
Electrospray-assisted laser desorption ionization (ELDI) is a technique which combines laser desorption with subsequent electrospray ionization. It is useful for directly detecting small and large molecules in solid or liquid samples under ambient conditions.
Min-Zong, Huang, Siou-Sian, Jhang, Chun-Nian, Cheng, Sy-Chyi, Cheng, Jentaie, Shiea   +4 more
openaire   +2 more sources

Investigation on the Role of Pneumatic Aspects in Electrospray, Desorption Electrospray Surface Ionization and Surface-Activated Chemical Ionization

European Journal of Mass Spectrometry, 2012
This review reports the results of some studies carried out by us on the role of pneumatic aspects in electrospray and desorption electrospray surface ionization, with the aim of proposing some relevant aspects of the mechanisms involved in these ionization methods.
Seraglia R, Molin L, Isak I, Traldi P
openaire   +3 more sources

Electrospray Laser Desorption Ionization

2019
Electrospray laser desorption ionization (ELDI) combines the features of both electrospray ionization and laser desorption. It allows direct, sensitive, and rapid analyses of chemical compounds on the sample surfaces. Chemical and biological compounds dissolved in polar and nonpolar solvents can also be characterized directly by ELDI-mass spectrometry (
openaire   +1 more source

Targeted metabolomic analysis of Escherichia coli by desorption electrospray ionization and extractive electrospray ionization mass spectrometry

Analytical Biochemistry, 2008
Desorption electrospray ionization (DESI) was utilized to monitor the presence of targeted central carbon metabolites within bacterial cell extracts and the quench supernatant of Escherichia coli. The targeted metabolites were identified through tandem mass spectrometry (MS/MS) product ion scans using collision-induced dissociation in the negative ion ...
Ayanna U, Jackson, Sean R, Werner, Nari, Talaty, Yishu, Song, Karinna, Campbell, R Graham, Cooks, John A, Morgan   +6 more
openaire   +2 more sources

Electrospray Laser Desorption Ionization Mass Spectrometry

2014
Electrospray laser desorption ionization mass spectrometry (ELDI/MS), an ambient mass spectrometric technique that combines laser desorption with postionization via electrospray, was developed to rapidly characterize analytes ranging from small organic to large biomolecules. The technique requires essentially no sample pretreatment.
Min-Zong Huang, Siou-Sian Jhang, Ya-Ting Chan, Sy-Chi Cheng, Chun-Nian Cheng, Jentaie Shiea   +5 more
openaire   +1 more source

In Situ Trace Detection of Peroxide Explosives by Desorption Electrospray Ionization and Desorption Atmospheric Pressure Chemical Ionization

Analytical Chemistry, 2008
Desorption electrospray ionization (DESI) mass spectrometry is used for the rapid (
Ismael, Cotte-Rodríguez, Heriberto, Hernandez-Soto, Hao, Chen, R Graham, Cooks   +3 more
openaire   +2 more sources