Results 251 to 260 of about 38,846 (279)

Targeted metabolomic analysis of Escherichia coli by desorption electrospray ionization and extractive electrospray ionization mass spectrometry

Analytical Biochemistry, 2008
Desorption electrospray ionization (DESI) was utilized to monitor the presence of targeted central carbon metabolites within bacterial cell extracts and the quench supernatant of Escherichia coli. The targeted metabolites were identified through tandem mass spectrometry (MS/MS) product ion scans using collision-induced dissociation in the negative ion ...
Ayanna U, Jackson, Sean R, Werner, Nari, Talaty, Yishu, Song, Karinna, Campbell, R Graham, Cooks, John A, Morgan   +6 more
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In Situ Trace Detection of Peroxide Explosives by Desorption Electrospray Ionization and Desorption Atmospheric Pressure Chemical Ionization

Analytical Chemistry, 2008
Desorption electrospray ionization (DESI) mass spectrometry is used for the rapid (
Ismael, Cotte-Rodríguez, Heriberto, Hernandez-Soto, Hao, Chen, R Graham, Cooks   +3 more
openaire   +2 more sources

Desorption electrospray ionization and other ambient ionization methods: current progress and preview

The Analyst, 2010
Mass spectrometry allows rapid chemical analysis of untreated samples in the ambient environment. This is a result of recent rapid progress in ambient ionization techniques. The most widely studied of these new methods, desorption electrospray ionization (DESI), uses fast-moving solvent droplets to extract analytes from surfaces and propel the ...
Demian R, Ifa, Chunping, Wu, Zheng, Ouyang, R Graham, Cooks   +3 more
openaire   +2 more sources

Ambient molecular imaging by desorption electrospray ionization mass spectrometry

Nature Protocols, 2008
Desorption electrospray ionization (DESI) allows the direct analysis of ordinary objects or pre-processed samples under ambient conditions. Among other applications, DESI is used to identify and record spatial distributions of lipids and drug molecules in biological tissue sections.
Justin M, Wiseman, Demian R, Ifa, Andre, Venter, R Graham, Cooks   +3 more
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Analysis and Mechanisms of Cyclotrimethylenetrinitramine Ion Formation in Desorption Electrospray Ionization

Analytical Chemistry, 2009
The general ion chemistry of the explosive molecule cyclotrimethylenetrinitramine (RDX) was studied with an atmospheric pressure ionization mass spectrometer (API-MS) fitted with a desorption electrospray ionization (DESI) source. Explosive molecule chemistry within trace detection techniques such as ion mobility spectrometry (IMS) is an area of ...
Christopher, Szakal, Tim M, Brewer
openaire   +2 more sources

Desorption electrospray ionization mass spectrometry for the analysis of pharmaceuticals and metabolites

Rapid Communications in Mass Spectrometry, 2005
Abstract The performance of desorption electrospray ionization (DESI) in the analysis of a group of pharmaceuticals and their glucuronic acid conjugates is reported. The suitability of different sprayer solvents and different surfaces was examined.
Tiina J, Kauppila, Justin M, Wiseman, Raimo A, Ketola, Tapio, Kotiaho, R Graham, Cooks, Risto, Kostiainen   +5 more
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Electrospray Laser Desorption Ionization Mass Spectrometry

2014
Electrospray laser desorption ionization mass spectrometry (ELDI/MS), an ambient mass spectrometric technique that combines laser desorption with postionization via electrospray, was developed to rapidly characterize analytes ranging from small organic to large biomolecules. The technique requires essentially no sample pretreatment.
Min-Zong Huang, Siou-Sian Jhang, Ya-Ting Chan, Sy-Chi Cheng, Chun-Nian Cheng, Jentaie Shiea   +5 more
openaire   +1 more source

Infrared laser-assisted desorption electrospray ionization mass spectrometry

The Analyst, 2008
We have used an infrared laser for desorption of material and ionization by interaction with electrosprayed solvent. Infrared laser-assisted desorption electrospray ionization (IR LADESI) mass spectrometry was used for the direct analysis of water-containing samples under ambient conditions.
Yohannes H, Rezenom, Jianan, Dong, Kermit K, Murray   +2 more
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Carbohydrate and steroid analysis by desorption electrospray ionization mass spectrometry

Chemical Communications, 2008
Desorption electrospray ionization mass spectrometry (DESI-MS) is applied to the analysis of carbohydrates and steroids; the detection limits are significantly improved by the addition of low concentrations of salts to the spray solvent.
Tiina J, Kauppila, Nari, Talaty, Ayanna U, Jackson, Tapio, Kotiaho, Risto, Kostiainen, R Graham, Cooks   +5 more
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Imaging of Lipids in Atheroma by Desorption Electrospray Ionization Mass Spectrometry

Analytical Chemistry, 2009
One of the hallmarks of atherosclerosis is the accumulation of lipoproteins within the wall of blood vessels. The lipid composition can vary among atheroma, even within a single individual, and is also dynamic, changing as the lesion progresses.
Nicholas E, Manicke, Marcela, Nefliu, Chunping, Wu, John W, Woods, Vladimir, Reiser, Ronald C, Hendrickson, R Graham, Cooks   +6 more
openaire   +2 more sources