Results 61 to 70 of about 11,274 (262)
Tourists’ profile and perceptions of a destination brand essence: KwaZulu-Natal, South Africa. [PDF]
African Journal of Hospitality, Tourism and Leisure, 2019 Tourism destination brand essence entails the functional and emotional benefits that tourists enjoy for visiting the destination. This study explored how tourists perceive the destination brand essence of KwaZulu-Natal in South Africa.
Prof. Ikechukwu O. Ezeuduji +1 more
doaj
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Destination Evaluation Attributes for Tourists in Hotel and Non-Hotel Accommodation in Spain
Administrative SciencesAccommodation constitutes a key element in the competitiveness of a destination. However, there is limited information on how overnight tourists evaluate the destination according to the type of accommodation.
Elena Sánchez-Vargas +3 more
doaj +1 more source
Lake-Destination Image Attributes: Content Analysis of Text and Pictures
, 2015 Abstract Lake tourism is a growing academic sub-field of tourism studies with an emerging body of literature. However, little research attention has been given to lake-destinations’ projected or perceived tourism images. Specifically, there has been a scarcity of literature investigating the variables involved in the formation of a ...
Correia, Antónia +3 more
openaire +6 more sources
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Molecular Oncology, EarlyView.The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
Destination Attributes of Memorable Chinese Rural Tourism Experiences: Impact on Positive Arousal, Memory and Behavioral Intention. [PDF]
Psychol Res Behav Manag, 2022 Huang R, Bu HM.
europepmc +1 more source
FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source