COVID-19 risk perception and tourist satisfaction: A mixed-method study of the roles of destination image and self-protection behavior. [PDF]
Front Psychol, 2022 Zhou B +4 more
europepmc +1 more source
Threonine 348 regulates the subcellular localization of PTEN
FEBS Open Bio, EarlyView.Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley +1 more source
FEBS Open Bio, EarlyView.The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
The mediation of perceived risk's impact on destination image and travel intention: An empirical study of Chengdu, China during COVID-19. [PDF]
PLoS One, 2022 Jiang X, Qin J, Gao J, Gossage MG.
europepmc +1 more source
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
FEBS Open Bio, EarlyView.Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source
Do you dare to travel to China? An examination of China's destination image amid the COVID-19. [PDF]
Tour Manag Perspect, 2021 Lu Q, Atadil HA.
europepmc +1 more source
Gap analysis between online destination image and perceived destination image [PDF]
The study represents an exploratory attempt to capture Margate’s projected and perceived destination image and to identify and analyse any discrepancies between them. The perceived image of Margate was identified through the analysis of a variety of secondary data such as Kent Tourism Board and articles published in popular travel magazines, while ...
Iordanova, Elitza, Penka, Uzunova
openaire
FEBS Open Bio, EarlyView.Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata +3 more
wiley +1 more source
Outbound medical tourists: The interplay of perceived quality, length of stay, group-size, post-visit destination image and revisit intention. [PDF]
PLoS One, 2022 Rahman I, Martin DS, Liu S.
europepmc +1 more source