Results 61 to 70 of about 405,906 (303)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The Impact of a Local Well-Being Philosophy on Revisit Intentions to Bali Among Digital Nomads
Tourism and HospitalityThe level of success in tourism is gauged by several metrics; however, the most widely used is the level of tourist arrivals. However, this research answered the call for greater investigation of the impacts of qualitative factors and intangible cultural–
Hanugerah Kristiono Liestiandre +4 more
doaj +1 more source
Destination image, satisfaction and destination and loyalty in cruise tourism: the case of Málaga (Spain) [PDF]
, 2016 Over the past decades cruise tourism is a sector that has experienced a tremendous growth around the globe. The relations that are established between the different agents that interact in this industry, passengers, crew and residents are crucial for ...
Bermudez-Gonzalez, Guillermo Jose +2 more
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Pre-trip vs. post-trip destination image variations: A case of inbound tourists to Tanzania [PDF]
, 2016 Despite the conceptual indications of destination image to vary with factors like travel status and tourist behaviour, there are few studies that have empirically researched the variations in destination image particularly in emerging destinations like ...
Dev Jani, Winnie Nguni
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
PLoS ONE, 2023 Tourism destinations are the important research objects of tourism geography. And destination songs, as a media of tourism destination image, play a very important role in it.
Long Wei +4 more
doaj
Destination Branding - Tracking Brand Equity for a Competitive Set of Near-Home Destinations [PDF]
, 2008 In the emerging literature related to destination branding, little has been reported about performance metrics. The focus of most research reported to date has been concerned with the development of destination brand identities and the implementation of ...
Pike, Steven
core +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
SAGE OpenDestination image and sensory impression are crucial to examine the tourist experience and behavioral intention. However, substantial knowledge gaps exist regarding how sensory impressions affect destination images and their mediating role in behavioral ...
Qiwen Zheng, Suraiyati Rahman
doaj +1 more source