Results 51 to 60 of about 114,759 (302)

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

THE IMPACT OF AGROTOURISM DESTINATION IMAGE ON TOURIST’S LOYALTY IN ZAGHOUAN, TUNISIA: MODERATING ROLE OF VISIT’S EXPERIENCE [PDF]

open access: yesGeo Journal of Tourism and Geosites
This study tests the influence of destination image on loyalty. It also examines the moderation effect of visitors’ experiences in the link between the two main components of destination image and loyalty.
Abu Elnasr E. SOBAIH   +3 more
doaj   +1 more source

The tourist experience: Exploring the relationship between tourist satisfaction and destination loyalty [PDF]

open access: yes, 2010
Previous studies show that the quality of the tourist experience is aff ected by a large set of factors, many of which not directly related to the acquisition of specifi c products or services.
Manuela Guerreiro, Maria   +3 more
core   +1 more source

Destination Motivation, Cultural Orientation, and Adaptation: International Students’ Destination-Loyalty Intention

open access: yesJournal of International Students, 2018
This study aims to understand factors predicting destination-loyalty intention in international education. A sample of 378 long-term (n=195) and short-term (n=183) international students participated in the study carried out in 2014 through an on-line survey at the University of Bergen, Norway.
Jamaludin, Nor Lelawati   +2 more
openaire   +4 more sources

The Influence of Destination Experience on Destination Loyalty in an Emerging Economy

open access: yesPakistan Journal of Commerce and Social Sciences, 2022
Destination loyalty has gained prominence because of the growing competition among tourist destinations. This study aims to test the influence of destination experiences (experience authenticity and experience quality) on destination loyalty. Further, tourist engagement was tested as a mediator between destination experiences and loyalty.
Din, Taskeen ud   +2 more
openaire   +2 more sources

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Customer empowerment in tourism through Consumer Centric Marketing (CCM) [PDF]

open access: yes, 2007
We explain Consumer Centric Marketing (CCM) and adopt this new technique to travel context. Benefits and disadvantages of the CCM are outlined together with warnings of typical caveats Value: CCM will be expected as the norm in the travel industry by ...
Buhalis, Dimitrios   +2 more
core   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Destination love in Asia: Understanding the role of experiences and perceived value in building tourist loyalty

open access: yesAsian Management and Business Review
This study proposes an integrated model to investigate how destination experience, destination love, and perceived value drive tourist loyalty, underpinned by attachment theory and expectancy-value theory.
Lilik Wahyudi, Endang Hariningsih
doaj   +1 more source

Tourism destination image, satisfaction and loyalty: A study of the Dead Sea in Jordanian curative tourism [PDF]

open access: yes, 2010
The aim of this paper is to explore the relationship between three key variables, namely image, satisfaction and loyalty in curative tourism industry in Jordan.
Alqurneh, Majid   +2 more
core  

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