Results 71 to 80 of about 114,759 (302)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Triggers For Destination Brand Loyalty Of Millennial Visitors To Natural Tourism Destinations

open access: yesJurnal Manajemen
This research investigates triggers for destination brand loyalty of millennial visitors to natural tourism destinations. This research focuses on millennial visitors who have come to several natural tourist destinations in Southern Sumatra, with a ...
Heri Setiawan, Rini, Alditia Detmuliati
doaj   +1 more source

Between Self Congruity, Destination Relationship and Memorable Tourist Experience: An Empiric Study on the Loyalty of Tourist Destination

open access: yesJurnal Dinamika Manajemen, 2019
This study examines the driving factors that can enhance tourist destination loyalty. Respondents used were 184 domestic tourists who had traveled to Bali. Data were analyzed using Structural Equation Modeling.
Elia Ardyan, Utomo Wibisono
doaj   +1 more source

Kiosks in retailing: the quiet revolution [PDF]

open access: yes, 2003
Kiosks have the potential to be a significant application of IT in retailing, information provision and service delivery. This article discusses and analyses the application of kiosks as a channel for in-store service delivery.
Rowley, J., Slack, Frances
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

The tourist loyalty index: A new indicator for measuring tourist destination loyalty?

open access: yesJournal of Innovation & Knowledge, 2019
The measurement of loyalty is a topic of great interest for the marketing academic literature. The relation that loyalty has with the results of organizations has been tested by numerous studies and the search to retain profitable customers has become a ...
Francisco-José Cossío-Silva   +2 more
doaj   +1 more source

An empirical survey on perceived value from tourism destination based on brand equity model: A case study of Qeshm Island [PDF]

open access: yes, 2012
Tourism destination brand equity is defined as all assets (or debts) of brands provided with name and symbol of tourism destination to make changes in value services of experiences. In many cases, brand equity is more than physical assets.
Vahid Qaemi
core  

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Visitors' experience in a modern art museum: a structural equation model [PDF]

open access: yes, 2010
This study aims to provide a better understanding on the museum experience by studying visitors’ motivation, satisfaction and likelihood to return to the Museum for Modern and Contemporary Art (MART) of Rovereto (Italy). The empirical data were obtained
Brida, Juan Gabriel   +2 more
core  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

open access: yesFEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani   +6 more
wiley   +1 more source

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