Results 111 to 120 of about 448,416 (286)
Managerial strategies to reduce stress and brain drain in tourism through moral values
Purpose: This research explores effective managerial practices to reduce brain drain in tourism by promoting moral values such as compassion and empathy.
Ana Leal-Solís +3 more
doaj +1 more source
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
A GLOBAL DATABASE OF DOMESTIC AND INTERNATIONAL TOURIST NUMBERS AT NATIONAL AND SUBNATIONAL LEVEL [PDF]
We present a new, global data base on tourist destinations. The data base differs from other data bases in that it includes both domestic and international tourists; and it contains data, for the most important destinations, data at national level as ...
Andrea Bigano +4 more
core
HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley +1 more source
Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source
STOCHASTIC CHOICE ANALYSIS OF TOURISM DESTINATIONS [PDF]
The analysis of tourist destination choice, defined by intra-country administrative units and by product types "coastal/inland and village/city", permits the characterisation of tourist flow behaviour, which is fundamental for public planning and ...
Francisco J. Mas, Juan Luis Nicolau
core
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Digital marketing in tourism: the role of social media and online platforms in shaping tourist flows
The article is devoted to the study of problematic issues in the development of digital marketing in tourism, in particular the role of social media and digital platforms in shaping tourist flows.
Halyna Tarasiuk +3 more
doaj +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source

