Results 61 to 70 of about 448,416 (286)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Economic migration and challenges in an emerging Eastern European destination country: evidence about immigrant labor market integration in Romania

open access: yesSocial Change Review, 2018
In this paper we aim to investigate the effects and outcomes of the integration system and reveal through data analysis the experiences of immigrants coming to Romania.
Oltean Ovidiu, Găvruș Georgiana
doaj   +1 more source

Conceptualising tourist based brand-equity pyramid: an application of Keller brand pyramid model to destinations

open access: yesTourism and Hospitality Management, 2017
Purpose – Different scales available for measuring the brand-equity of destinations are found to be much tourist centric and did not present a holistic view regarding building sustainable customer based brand-equity for destinations. Current study aim at
Anish Yousaf , Insha Amin, Anil Gupta
doaj   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Destinations of leavers from Scottish schools : 2006/07 [PDF]

open access: yes, 2007
"This Statistics Publication Notice presents national and Education Authority level information on the destinations of young people leaving Scottish schools (publicly funded and grant-aided secondary schools) and updates the publication “Destinations of

core  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Projected Images of Major Chinese Outbound Destinations [PDF]

open access: yes, 2011
This study aimed to explore the projected images of major outbound destinations based on popular travel magazines in China. Travel articles on Hong Kong, Macau, Japan, South Korea, Vietnam and Taiwan from 2006 to 2008 were content analyzed.
Ashworth G. J.   +22 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Travel motivations of tourists visiting Kruger National Park

open access: yesKoedoe: African Protected Area Conservation and Science, 2008
The Kruger National Park (KNP) one of the largest conservation areas in South Africa, attracts in excess of one million visitors a year and is regarded as an icon destination in international tourism. Since this park attracts more tourists than any other
Peet van der Merwe, Melville Saayman
doaj   +1 more source

Descriptive Study On Destination Image Perception By The Surabaya Domestic Tourists [PDF]

open access: yes, 2012
Tourist destinations is an important sector role inthe economy. For that a tourist destination should be handled properly in order to meet the expectations of tourists and the community.
Widjaja, Fitri Novika
core  

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