Results 91 to 100 of about 952 (119)

Integrated transcriptomics uncovers an enhanced association between the prion protein gene expression and vesicle dynamics signatures in glioblastomas. [PDF]

BMC Cancer
Boccacino JM, Dos Santos Peixoto R, Fernandes CFL, Cangiano G, Sola PR, Coelho BP, Prado MB, Melo-Escobar MI, de Sousa BP, Ayyadhury S, Bader GD, Shinjo SMO, Marie SKN, da Rocha EL, Lopes MH.   +14 more
europepmc   +1 more source

Role of Tpm Isoforms Produced by the <i>TPM4</i> Gene in the Regulation of Actin Filament Dynamics by Cofilin. [PDF]

Biomolecules
Roman SG, Nefedova VV, Matyushenko AM.
europepmc   +1 more source

Disulfidptosis: A Novel Prognostic Criterion and Potential Treatment Strategy for Diffuse Large B-Cell Lymphoma (DLBCL). [PDF]

Int J Mol Sci
Wang Y, Tsukamoto Y, Hori M, Iha H.
europepmc   +1 more source

Integration of Single-cell and bulk RNA sequencing data uncovers lymphatic metastasis-related prognostic genes and a predictive model in bladder cancer. [PDF]

Sci Rep
Yang B, Wei Y, Liu S, Wang J, Zhao X, Wang J, Fu Y, Wang C, Yang X.   +8 more
europepmc   +1 more source

Proteomic characterisation of matrix vesicles from primary osteoblasts indicates a mixed population with both exosomal and ectosomal routes of biogenesis

Dillon S, Clews C, Kurian D, Nudelman F, Farquharson C, Stephen LA.   +5 more
europepmc   +1 more source

Destrin, a mammalian actin-depolymerizing protein, is closely related to cofilin. Cloning and expression of porcine brain destrin cDNA.

Journal of Biological Chemistry, 1990
Destrin is a mammalian 19-kDa protein that rapidly depolymerizes F-actin in a stoichiometric manner. In this study, we isolated cDNA clones coding for destrin from a porcine brain cDNA library. The deduced amino acid sequence of destrin is 165 residues long and is very similar (71% identical) to that of cofilin, a widely distributed, pH-sensitive actin-
I Yahara, K Moriyama
exaly   +3 more sources

Effect of destrin mutations on the gene expression profile in vivo [PDF]

Physiological Genomics, 2008
Remodeling of the actin cytoskeleton through actin dynamics (assembly and disassembly of filamentous actin) is known to be essential for numerous basic biological processes. In addition, recent studies have provided evidence that actin dynamics participate in the control of gene expression.
Akihiro Ikeda, Sakae Ikeda
exaly   +3 more sources

Tertiary Structure of Destrin and Structural Similarity between Two Actin-Regulating Protein Families [PDF]

Cell, 1996
Destrin is an isoprotein of cofilin that regulates actin cytoskeleton in various eukaryotes. We determined the tertiary structure of destrin by triple-resonance multidimensional nuclear magnetic resonance. In spite of there being no significant amino acid sequence homology, we found that the folding of destrin was strikingly similar to that of repeated
Kenji Ogura, F Inagaki, I Yahara
exaly   +3 more sources

Destrin Contributes to Lung Adenocarcinoma Progression by Activating Wnt/β-Catenin Signaling Pathway [PDF]

Molecular Cancer Research, 2020
Abstract Lung cancer, especially lung adenocarcinoma, is one of the most common neoplasms worldwide. However, the mechanisms underlying its initiation, development, and metastasis are still poorly understood. Destrin (DSTN) is a member of ADF/cofilin family.
Qiao Ling
exaly   +3 more sources

Proteomic Profiling Identifies an UV-Induced Activation of Cofilin-1 and Destrin in Human Epidermis [PDF]

Journal of Investigative Dermatology, 2005
The human skin is the only line of defense against UV radiation. A series of responses to protect the skin are induced by UV radiation. In this study, a proteomic approach was used to study these responses. We have performed high-resolution two-dimensional polyacrylamide gel electrophoresis (2D-PAGE) analysis of (solar simulated) UV-exposed ...
Paul Hensbergen, Cornelis Tensen, Maria Ponec   +2 more
exaly   +3 more sources