Results 41 to 50 of about 952 (119)
BioFactors, Volume 50, Issue 2, Page 347-359, March/April 2024.Glucocorticoid‐induced osteoporosis (GIO) reduces bone formation, osteoblasts differentiation and function, and accelerates osteoblast and osteocyte apoptosis. Genistein induces bone remodeling through Wnt/β‐catenin pathway activation in osteoblast and osteocytes.
Federica Mannino +5 more
wiley +1 more source
, 2023 <div>Abstract<p>Lung cancer, especially lung adenocarcinoma, is one of the most common neoplasms worldwide. However, the mechanisms underlying its initiation, development, and metastasis are still poorly understood. Destrin (DSTN) is a member of ADF/cofilin family.
Feng Lu +13 more
openaire +1 more source
Changes in the Proteome of the Circle of Willis during Aging Reveal Signatures of Vascular Disease
Oxidative Medicine and Cellular Longevity, Volume 2024, Issue 1, 2024.Approximately 70% of all strokes occur in patients over 65 years old, and stroke increases the risk of developing dementia. The circle of Willis (CoW), the ring of arteries at the base of the brain, links the intracerebral arteries to one another to maintain adequate cerebral perfusion.
Vikram Subramanian +6 more
wiley +1 more source
Experimental Cell Research, 1994 Using separation of total cellular proteins by two dimensional (2-D) gel electrophoresis (isoelectric focusing/SDS-PAGE) we have characterized two regulated proteins, p21 and p19, in dog thyroid cells. We have used the same 2-D gel technique to purify these proteins before their trypsin cleavage and partial sequencing.
Saito, T +4 more
openaire +3 more sources
Abnormal epithelial homeostasis in the cornea of mice with a destrin deletion.
Molecular vision, 2008 Dstn(corn1) mice lack normal destrin expression and develop corneal abnormality shortly after birth such as epithelial hyperplasia and total vascularization. Thus, the mice serve as a model for ocular surface disorders. To determine the nature of epithelial defects, we examined whether epithelial homeostasis is altered in these corneas.Dstn(corn1) mice
W, Zhang +4 more
openaire +1 more source
Identification of Two 17-kDa Rat Parotid Gland Phosphoproteins, Subjects for Dephosphorylation upon β-Adrenergic Stimulation, as Destrin- and Cofilin-like Proteins [PDF]
Journal of Biological Chemistry, 1995 We previously reported that when 32Pi-loaded rat parotid slices are incubated with the beta-adrenergic agonist isoproterenol, the level of a soluble 32P-labeled 17-kDa protein (pp17) decreases rapidly (Kanamori, T., and Hayakawa, T. (1982) Biochem. Int. 4, 517-523).
T, Kanamori +3 more
openaire +2 more sources
, 2023 <p>Supplementary Table 1. The differentially expressed proteins of normal and early - stage lung cancer tissues identified by LC-MS/MS analysis (N: normal; T: tumor).</p>
Feng Lu +13 more
openaire +1 more source
Journal of Biological Chemistry, 1992 Cofilin and destrin are two related low molecular weight mammalian actin-binding proteins. Cofilin is an F-actin side-binding and pH-dependent actin-depolymerizing protein, and destrin is a pH-independent actin-depolymerizing protein. We have introduced a few point mutations within an actin-binding sequence of cofilin.
K, Moriyama +4 more
openaire +2 more sources
, 2023 <p>Supplementary Table 2.Proteins chosen for immunohistochemistry and Western blot validation. Supplementary Table 3. Correlations between clinicopathologic factors and destrin expression. Supplementary Table 4. Multivariate Cox regression analysis of survival rate in 86 lung. Supplementary Table 5.
Feng Lu +13 more
openaire +1 more source