Results 21 to 30 of about 952 (119)

Spontaneous Corneal Hem- and Lymphangiogenesis in Mice with Destrin-Mutation Depend on VEGFR3 Signaling [PDF]

The American Journal of Pathology, 2005
Lymphangiogenesis, the formation of new lymphatic vessels, is important for tumor metastasis and induction of immunity to peripheral antigens including organ transplants. We herein describe a novel mouse model of spontaneous, secondary lymphangiogenesis in the normally avascular cornea.
Cursiefen, C, Ikeda, S, Nishina, P M, Smith, R S, Ikeda, A, Jackson, D, Mo, J S, Chen, L, Dana, M R, Pytowski, B, Kruse, F E, Streilein, J W   +11 more
openaire   +2 more sources

Molecular and functional profiling of apical versus basolateral small extracellular vesicles derived from primary human proximal tubular epithelial cells under inflammatory conditions

Journal of Extracellular Vesicles, Volume 10, Issue 4, February 2021., 2021
Abstract Proximal tubular epithelial cells (PTEC) are central players in inflammatory kidney diseases. However, the complex signalling mechanism/s via which polarized PTEC mediate disease progression are poorly understood. Small extracellular vesicles (sEV), including exosomes, are recognized as fundamental components of cellular communication and ...
Xiangju Wang, Ray Wilkinson, Katrina Kildey, Jacobus P. J. Ungerer, Michelle M. Hill, Alok K. Shah, Ahmed Mohamed, Mriga Dutt, Jeffrey Molendijk, Helen Healy, Andrew J. Kassianos   +10 more
wiley   +1 more source

Up‐regulation of cofilin‐1 in cell senescence associates with morphological change and p27kip1‐mediated growth delay

Aging Cell, Volume 20, Issue 1, January 2021., 2021
Triggers of senescence, such as replicative stress or oxidative stress, can induce the expression of cofilin‐1 to influence of cell morphology. Up‐regulated cofilin‐1 would enhance the expression of p27kip1 gene by suppressing the TEAD‐1 that transrepresses p27kip1 and lead to senescence‐associated growth delay.
Cheng‐Han Tsai, Chun‐Yuan Chang, Bing‐Ze Lin, Yu‐Lou Wu, Meng‐Hsiu Wu, Liang‐Tin Lin, Wen‐Chien Huang, Jonathan D. Holz, Tzong‐Jen Sheu, Jhih‐Shian Lee, Richard N. Kitsis, Pei‐Han Tai, Yi‐Jang Lee   +12 more
wiley   +1 more source

Human cord plasma proteomic analysis reveals sexually dimorphic proteins associated with intrauterine growth restriction. [PDF]

Proteomics
Abstract Intrauterine growth restriction (IUGR) is associated with increased risk of cardiometabolic disease later in life and has been shown to affect female and male offspring differently, but the mechanisms remain unclear. The purpose of this study was to identify proteomic differences and metabolic risk markers in IUGR male and female neonates when
Akinyemi AJ, Du XQ, Aguilan J, Sidoli S, Hirsch D, Wang T, Reznik S, Fuloria M, Charron MJ.   +8 more
europepmc   +2 more sources

Effects of destrin pathway mutations on the gene expression profile

Genetics and Molecular Research, 2014
This study aimed to explore the interaction and crosstalk between pathways in response to destrin mutations. All the pathways from the MINT database were downloaded, a protein-protein interaction network was then constructed, and the crosstalk between pathways was investigated, in particular, the overlap of 2 significant pathway analysis results.
J N, Xu, X, Liu, H, Wang, C M, Hu, Q H, Luo, Q Q, Zhou   +5 more
openaire   +2 more sources

Inhibiting actin depolymerization enhances osteoblast differentiation and bone formation in human stromal stem cells

Stem Cell Research, 2015
Remodeling of the actin cytoskeleton through actin dynamics is involved in a number of biological processes, but its role in human stromal (skeletal) stem cells (hMSCs) differentiation is poorly understood.
Li Chen, Kaikai Shi, Charles Edward Frary, Nicholas Ditzel, Huimin Hu, Weimin Qiu, Moustapha Kassem   +6 more
doaj   +1 more source

Importance of amylases for physiological quality in maize seeds

Biotemas, 2017
Seed quality is the result of the sum of genetic, physical, physiological and sanitary attributes that affect seed ability to perform vital functions related to germination, vigor, and longevity.
Camila Aparecida Lopes, Maria Laene Moreira de Carvalho, Heloisa Oliveira dos Santos, Dayliane Bernardes de Andrade   +3 more
doaj   +1 more source

Actin depolymerization enhances adipogenic differentiation in human stromal stem cells

Stem Cell Research, 2018
Human stromal stem cells (hMSCs) differentiate into adipocytes that play a role in skeletal tissue homeostasis and whole body energy metabolism. During adipocyte differentiation, hMSCs exhibit significant changes in cell morphology suggesting changes in ...
Li Chen, Huimin Hu, Weimin Qiu, Kaikai Shi, Moustapha Kassem   +4 more
doaj   +1 more source

Characterization of Destrins with Different Dextrose Equivalents [PDF]

Molecules, 2010
Dextrins are widely used for their functional properties and prepared by partial hydrolysis of starch using acid, enzymes, or combinations of both. The physiochemical properties of dextrins are dependent on their molecular distribution and oligosaccharide profiles.
Sun, Junliang, Zhao, Ruixiang, Zeng, Jie, Li, Guanglei, Li, Xinhua   +4 more
openaire   +3 more sources

Role of ghrelin in the pancreatic exocrine secretion via mitogen-activated protein kinase signaling in rats

Journal of Animal Science and Technology, 2017
Background This study was performed to investigate the impact of exogenous ghrelin on the pancreatic α-amylase outputs and responses of pancreatic proteins to ghrelin that may relate to pancreatic exocrine.
Kyung-Hoon Lee, Jae-Sung Lee, Tao Wang, Jin-Ju Oh, Sanggun Roh, Hong-Gu Lee   +5 more
doaj   +1 more source