Results 41 to 50 of about 550,291 (266)

THE FIELD OF RECENT TECTONIC STRESSES IN CENTRAL AND SOUTH-EASTERN ASIA

open access: yesГеодинамика и тектонофизика, 2015
The publication presents results of the study aimed at reconstruction of recent crustal stresses for Central and South-Eastern Asia with application of the method of cataclastic analysis of displacements caused by ruptures, which was proposed by Yu.L ...
Yu. L. Rebetsky, R. S. Alekseev
doaj   +1 more source

Distribution of the wolf (Canis lupus) in the steppe zone of Ukraine at the turn of the 20th and 21st centuries and its population dynamics

open access: yesTheriologia Ukrainica, 2023
The article presents data on the extirpation of the wolf in southern Ukraine in the 18th to the 20th century, which was financially supported by landowners and the state.
Anatoliy Volokh
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Research on Vertical Separation–Collision Effects and Pier Failure Mechanism of Multi-Span Continuous Beam Bridges

open access: yesBuildings
In near-fault regions, intense vertical seismic excitation combined with the widespread lack of tensile capacity in bridge bearings can readily induce vertical separation between piers and girders.
Chao Yang   +8 more
doaj   +1 more source

WHY WE CANNOT PREDICT STRONG EARTHQUAKES IN THE EARTH’S CRUST

open access: yesГеодинамика и тектонофизика, 2015
In the past decade, earthquake disasters caused multiple fatalities and significant economic losses and challenged the modern civilization. The wellknown achievements and growing power of civilization are backstrapped when facing the Nature. The question
Iosif L. Gufeld   +2 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

The safe operations modes substantiation for water source wellbores of the Vadelypskoye deposit

open access: yesGeoresursy, 2018
The sand production problem for the water sources wellbores at the Vadelypskoye oilfield that is located in Hanty-Mansy region of Russia is considered. The serious issue during field operations is the open wellbore wall destruction even if low drawdown ...
A.V. Seryakov   +3 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

Influence of Carbonization of Concrete Surfaces on their Adhesion with Freshly-Laid Concrete

open access: yesНаука и техника, 2021
During operation, concrete and reinforced concrete structures are exposed to the aggressive environment of carbon dioxide. During the reconstruction and overhaul of the berthing facilities in the coastal zone of the seas of the Far East, a weak bond ...
V. V. Molodin   +2 more
doaj   +1 more source

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