Results 41 to 50 of about 757,509 (314)
Methodology and features of a computational experiment to assess the resource of responsible engineering facilities [PDF]
Известия Саратовского университета. Новая серия: Математика. Механика. ИнформатикаThe problem of obtaining estimates of the strength and resource characteristics of critical engineering infrastructure facilities under operational multiparametric nonstationary thermomechanical impacts is considered.
Volkov, Ivan A. +3 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
The application of epoxy resin polymers by laser induction technologies
Science and Engineering of Composite MaterialsThe fabrication of robust and high-performance graphene-based electrodes on engineering plastics has garnered significant attention in recent years. In this study, we present a novel methodology to produce porous graphene structures derived from epoxy ...
Yu Chao +6 more
doaj +1 more source
THE FIELD OF RECENT TECTONIC STRESSES IN CENTRAL AND SOUTH-EASTERN ASIA
Геодинамика и тектонофизика, 2015 The publication presents results of the study aimed at reconstruction of recent crustal stresses for Central and South-Eastern Asia with application of the method of cataclastic analysis of displacements caused by ruptures, which was proposed by Yu.L ...
Yu. L. Rebetsky, R. S. Alekseev
doaj +1 more source
Innovation and job creation and destruction : evidence from Spain [PDF]
, 2001 In this paper we examine the effect of innovation on job creation and job destruction in Spanish manufacturing. Our empirical analysis is based on firm-level longitudinal data from which we have information on employment and innovation activity.
Alonso Borrego, César +3 more
core +1 more source
Heritage destruction and its impact in Scandinavia and the Baltic region during the Second World War
, 2023 In the Second World War, aerial warfare was seen as the single greatest threat to a nation's cultural property. Precautions were thus made both before the outbreak of the war and during its development to protect immovable and movable cultural property ...
Legnér, Mattias,
core +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Capital accumulation in a model of growth and creative destruction [PDF]
Capital accumulation and creative destruction is modeled together with risk-averse households. The novel aspect - risk-averse households - allows to use well-known models not only for analyzing long-run growth as in the literature but also short-run ...
Klaus WAELDE
core +4 more sources
BuildingsIn near-fault regions, intense vertical seismic excitation combined with the widespread lack of tensile capacity in bridge bearings can readily induce vertical separation between piers and girders.
Chao Yang +8 more
doaj +1 more source