Results 51 to 60 of about 757,509 (314)
WHY WE CANNOT PREDICT STRONG EARTHQUAKES IN THE EARTH’S CRUST
In the past decade, earthquake disasters caused multiple fatalities and significant economic losses and challenged the modern civilization. The wellknown achievements and growing power of civilization are backstrapped when facing the Nature. The question
Iosif L. Gufeld +2 more
doaj +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
The article presents data on the extirpation of the wolf in southern Ukraine in the 18th to the 20th century, which was financially supported by landowners and the state.
Anatoliy Volokh
doaj +1 more source
The incidence of mycotic infections of paranasal sinuses is on the rise. Aspergillosis is the commonest fungal infection involving the nose and paranasal sinuses. This disease has a varied presentation ranging from the allergic form to the more deadly invasive or destructive form.
Surinder K, Singhal +4 more
openaire +3 more sources
Intentional Destruction of Cultural Heritage and Reparations
The cultural heritage should be protected all the time. None of the high contracting parties in the hostilities could destroy or even use it as their shield.
Vrdoljak, AF
core +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The safe operations modes substantiation for water source wellbores of the Vadelypskoye deposit
The sand production problem for the water sources wellbores at the Vadelypskoye oilfield that is located in Hanty-Mansy region of Russia is considered. The serious issue during field operations is the open wellbore wall destruction even if low drawdown ...
A.V. Seryakov +3 more
doaj +1 more source
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source

