Results 51 to 60 of about 652,613 (355)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Application of IMA and H-FABP in Forensic Diagnosis of Sudden Cardiac Death [PDF]
Fayixue Zazhi, 2017 Acute myocardial ischemia is the most common cause of sudden cardiac death. The diagnosis of early myocardial ischemia is a hot point in forensic medicine, which is also an early and important part for a prevention against myocardial infarction ...
ZHU ZE-LEI, WANG PENG, YOU JIA-BIN, ET AL.
doaj +1 more source
La virtud del desprendimiento o señorío según Leonardo Polo
Franciscanum, 2021 Based on the three hierarchically different levels that Leonardo Polo distinguishes in man, corporeal nature, immaterial essence (intelligence, will and personality) and the act of being personal, the poverty can affect one or another layer ...
Juan Fernando Sellés Dauder
doaj +1 more source
Modelling of the growth and detachment of a vapour bubble and the effect of a electric field in the nucleate boiling regime [PDF]
, 2006 A comprehensive model predicting the deformation, growth and detachment of a vapour bubble in the nucleate boiling regime with an applied electric field is described in this paper.
Hristov, Y +4 more
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Role Of Point Of Care Ultrasound In The Diagnosis Of Retinal Detachment In The Emergency Department. [PDF]
, 2019 Ocular complaints represent up to 3% of all emergency department (ED) visits. These presentations can result in permanent vision loss if not promptly diagnosed and treated.
Ali, Qumber +4 more
core
Perceived Community Cohesion and the Stress Process in Youth [PDF]
, 2011 Using survey data from two youth samples, one rural and one urban, we examine the role and significance of perceived community cohesion in the stress process. In particular, we assess the extent to which community attachment and detachment are related to
Cohn, Ellen S +4 more
core +2 more sources
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Submarine slope failure offshore Uruguay - first results [PDF]
, 2010 New geophysical acquired during cruise M78 with RV “Meteor” in 2009 reveal a large-scale slope failure complex. Positioned between 1800 and 3300 m water depth, the slope failure affected an area of at least 1200 km2.
Anasetti, Andrea +6 more
core
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source