Results 141 to 150 of about 3,842,363 (279)

Studies into the detection of buried objects (particularly optical fibres) in saturated sediment. Part 4: experimental investigations into the acoustic detection of objects buried in saturated sediment

, 2007
This report is the fourth in a series of five, designed to investigate the detection oftargets buried in saturated sediment, primarily through acoustical or acoustics-relatedmethods.
Evans, R.C.P.
core   +1 more source

Modeling the impact of mass influenza vaccination and public health interventions on COVID-19 epidemics with limited detection capability. [PDF]

Math Biosci, 2020
Li Q, Tang B, Bragazzi NL, Xiao Y, Wu J.
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Mapping sustainable development in a capability perspective [PDF]

The importance of the notion of sustainable development has been advocated, among others, by Amartya Sen. In Sen’s view it is necessary to depart from the general strategy of defining sustainable development only in terms of fulfilment of needs and to ...
Enzo Di Giulio, Marco Grasso
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

High-performance 2D MoTe₂-based photodetectors with superior Vis-NIR detection capability. [PDF]

RSC Adv
Wang X, Zhou Q, Shen J, Lin L, Tu H, Zhang G.   +5 more
europepmc   +1 more source

A Host-Specific Blocking Primer Combined with Optimal DNA Extraction Improves the Detection Capability of a Metabarcoding Protocol for Canine Vector-Borne Bacteria. [PDF]

Pathogens, 2020
Huggins LG, Koehler AV, Schunack B, Inpankaew T, Traub RJ.   +4 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

UAV and UFB Detection Capability of an L-Band Long-Range Air Surveillance Radar: Geometric and RCS Constraints for LSS Targets. [PDF]

Sensors (Basel)
Braun A, Hegyi N.
europepmc   +1 more source