Results 101 to 110 of about 240,773 (297)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Canine-centered interface design: supporting the work of diabetes alert dogs [PDF]
, 2014 Many people with Diabetes live with the continuous threat of hypoglycaemic attacks and the danger of going into coma. Diabetic Alert Dogs are trained to detect the onset of an attack before the human handler they are paired with deteriorates, giving them
Guest, Claire +4 more
core +2 more sources
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Acute febrile illness is associated with Rickettsia spp infection in dogs [PDF]
, 2015 BACKGROUND: Rickettsia conorii is transmitted by Rhipicephalus sanguineus ticks and causes Mediterranean Spotted Fever (MSF) in humans. Although dogs are considered the natural host of the vector, the clinical and epidemiological significance of R ...
A Cascio +69 more
core +3 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Differential Effects of Aging on Behavior in Working and Untrained Companion Dogs [PDF]
Animal Behavior and CognitionAging related declines in cognition and behavior may have a detrimental impact on working dog performance and welfare. However, while aging related changes have been well documented in companion dogs, no work has determined if those findings generalize ...
Sarah Krichbaum, Lucia Lazarowski
doaj +1 more source
Top-Down Saliency Detection Driven by Visual Classification
, 2018 This paper presents an approach for top-down saliency detection guided by visual classification tasks. We first learn how to compute visual saliency when a specific visual task has to be accomplished, as opposed to most state-of-the-art methods which ...
Concetto Spampinato +5 more
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
First cases of canine dirofilariosis inSlovakia: a case report
Veterinární Medicína, 2005 Dogs from two locations in West Slovakiasuspected to have dirofilariosis were tested with the help of microfilariae detection, histochemical identification of microfilaria species and Dirofilaria immitis specific antigen detection in the blood serum. Six
V. Svobodova +3 more
doaj +1 more source
Recombinant subunit vaccines against Neospora caninum [PDF]
, 2007 The intracellular protozoan parasite Neospora caninum is an important cause of bovine abortion and congenital infection in many countries. Currently there is no effective control method available, and development of a vaccine has been suggested as a ...
Pinitkiatisakul, Sunan
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