Results 61 to 70 of about 3,695,100 (289)

Sniffer dogs performance is stable over time in detecting COVID-19 positive samples and agrees with the rapid antigen test in the field

Scientific Reports, 2023
Rapid antigen diagnostic (RAD) tests have been developed for the identification of the SARS-CoV-2 infection. However, they require nasopharyngeal or nasal swab, which is invasive, uncomfortable, and aerosolising.
Federica Pirrone, Patrizia Piotti, Massimo Galli, Roberto Gasparri, Aldo La Spina, Lorenzo Spaggiari, Mariangela Albertini   +6 more
doaj   +1 more source

A detection dog for obstructive sleep apnea

Sleep and Breathing, 2018
We sought to assess whether a dog can be trained to distinguish obstructive sleep apnea patients from healthy controls based on the olfactory detection of urine.Urine samples were collected from 23 adult male obstructive sleep apnea patients and from 20 voluntary adult male volunteers. Three dogs were trained through reinforced operant conditioning.Two
Bachour Adel, Koskinen Anni, Vaarno Jenni, Bäck Leif, Klockars Tuomas, Bachour Adel, Koskinen Anni, Vaarno Jenni, Bäck Leif, Klockars Tuomas   +9 more
openaire   +2 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Extinction of experimental Triatoma infestans populations following continuous exposure to dogs wearing deltamethrin-treated collars. [PDF]

, 2006
Dogs are domestic reservoir hosts of Trypanosoma cruzi, the etiological agent of Chagas disease. We evaluated the effect of deltamethrin-treated dog collars (DTDCs) over time on the population dynamics of Triatoma infestans, a main T. cruzi vector. Forty
Reithinger, Richard, Ceballos, Leonardo, Gürtler, Ricardo E, Stariolo, Raúl, Davies, Clive R   +4 more
core   +1 more source

Trained dogs can detect the odor of Parkinson's disease

Journal of Parkinson’s Disease
A definitive diagnostic test for Parkinson's disease (PD) remains elusive, so identification of potential biomarkers can facilitate diagnosis and early intervention.
Nicola Rooney, Drupad K Trivedi, Eleanor Sinclair, Caitlin Walton-Doyle, Monty Silverdale, Perdita Barran, Tilo Kunath, Steve Morant, Mark Somerville, Jayde Smith, Julie Jones-Diette, Jenny Corish, Joy Milne, Claire Guest   +13 more
doaj   +1 more source

Environmental and Physiological Factors Associated With Stamina in Dogs Exercising in High Ambient Temperatures

Frontiers in Veterinary Science, 2017
This IACUC approved study was performed to evaluate the environmental, physiological, and hematological components that contribute to stamina following successive bouts of exercise that included searching (5-min), agility (5-min), and ball retrieve (< ...
Patrick J. Robbins, Meghan T. Ramos, Brian M. Zanghi, Cynthia M. Otto   +3 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Detection and molecular characterization of sapoviruses in dogs

Infection, Genetics and Evolution, 2016
Caliciviruses are important human and animal pathogens. Novel caliciviruses have been identified recently in dogs, raising questions about their pathogenic role and concerns regarding their zoonotic potential. By screening stool samples of young or juvenile dogs using RT-PCR assays, sapoviruses (SaVs) were found in 7/320 (2.2%) samples of animals with ...
Bodnar, Livia, DI MARTINO, Barbara, DI PROFIO, FEDERICA, MELEGARI, IRENE, Lanave, Gianvito, Lorusso, Eleonora, Cavalli, Alessandra, Elia, Gabriella, Bányai, Krisztián, MARSILIO, Fulvio, Buonavoglia, Canio, Martella, Vito   +11 more
openaire   +3 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source