Results 201 to 210 of about 11,794,013 (339)

Compared with conventional PCR assay, qPCR assay greatly improves the detection efficiency of predation. [PDF]

Ecol Evol, 2020
Yang TB, Liu J, Chen J.
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Somatic mutation detection efficiency in EGFR: a comparison between high resolution melting analysis and Sanger sequencing. [PDF]

BMC Cancer, 2020
Joy RA, Thelakkattusserry SK, Vikkath N, Bhaskaran R, Krishnan S, Vasudevan D, Ariyannur PS.   +6 more
europepmc   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Impact of Device Architecture on Proton Detection Efficiency in 2D Perovskite Thick Film Detectors. [PDF]

Small
Napolitano G, Cepić S, Fratelli I, Chiari M, Fraboni B, Basiricò L.   +5 more
europepmc   +1 more source

Efficient MIMO Detection Methods

, 2014
For the past decades, the demand in transferring large amounts of data rapidly and reliably has been increasing drastically. One of the more promising techniques that can provide the desired performance is multiple-input multiple-output (MIMO) technology where multiple antennas are placed at both the transmitting and receiving side of the communication
openaire   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Effects of Microwave on Mortality and Detection Efficiency of Three Stored Grain Insect Adults in Stored Paddy, and on Grain Quality. [PDF]

Insects
Miao S, Zhou Y, Wang S, Yang Z, Guverinoma A, Zhao Y, Lu Y.   +6 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Surpassing 99% detection efficiency by cascading two superconducting nanowires on one waveguide with self-calibration. [PDF]

Light Sci Appl
Li ZG, Mao J, Zhou YJ, Guo JW, Chen S, Hao H, Huang YH, Ru SY, Liu NT, Liu Z, Deng J, Yang F, Tu XC, Zhang LB, Jia XQ, Chen J, Kang L, Wang J, Zhao QY, Gong Q, Wu PH.   +20 more
europepmc   +1 more source