Results 131 to 140 of about 8,972,343 (398)
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Alternative approach to community detection in networks
, 2009 The problem of community detection is relevant in many disciplines of science and modularity optimization is the widely accepted method for this purpose.
Dorso, C. O., Medus, A. D.
core +1 more source
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
, 2014 We continue our exploration of the nearly Peccei-Quinn symmetric limit shared by common singlet extensions of the Minimal Supersymmetric Standard Model. This limit has been established as a viable framework for studying sub-electroweak scale dark matter ...
Huang, Jinrui +3 more
core +2 more sources
The Case of the Limit of Detection
Brazilian Journal of Analytical Chemistry, 2022 Students learn early on in science courses that reliable results can only be achieved from accurate measurements. In some of the first general chemistry classes, but even more intensively in analytical chemistry classes, students are introduced to the concept of significant figures.
openaire +1 more source
Entanglement-enhanced quantum metrology: From standard quantum limit to Heisenberg limit [PDF]
Applied Physics ReviewsEntanglement-enhanced quantum metrology explores the utilization of quantum entanglement to enhance measurement precision. When particles in a probe are prepared into a suitable quantum entangled state, they may collectively accumulate information about ...
Jiahao Huang, Zhuang Min, Chaohong Lee
semanticscholar +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
On a generalization of the binomial distribution and its Poisson-like limit
, 2011 We examine a generalization of the binomial distribution associated with a strictly increasing sequence of numbers and we prove its Poisson-like limit. Such generalizations might be found in quantum optics with imperfect detection. We discuss under which
E. M. F. Curado +7 more
core +3 more sources
Tutorial: Basic principles, limits of detection, and pitfalls of highly sensitive SQUID magnetometry for nanomagnetism and spintronics [PDF]
, 2018 Martin Buchner +4 more
openalex +1 more source
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source