Results 41 to 50 of about 561,010 (268)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Ecology and Evolution, 2014 Theory recognizes that a treatment of the detection process is required to avoid producing biased estimates of population rate of change. Still, one of three monitoring programmes on animal or plant populations is focused on simply counting individuals ...
Vincenzo Gervasi +4 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Probability Estimation for People Detection. [PDF]
, 2003 This paper presents a probability method for detecting people in a static image. We simplify people as a torso and four limbs. The torso is fitted by a quadrangle, and each limb is fitted by one or two quadrangles depending on its pose. In order to find people, we should try to find a combination of quadrangles that must satisfy some geometric and ...
Sun, Qingjie, Wu, Enhua
openaire
Improved probability of detection of ecological “surprises” [PDF]
Proceedings of the National Academy of Sciences, 2010 Ecological “surprises” are defined as unexpected findings about the natural environment. They are critically important in ecology because they are catalysts for questioning and reformulating views of the natural world, help shape assessments of the veracity of a priori predictions about ecological trends and phenomena, and underpin ...
Likens, Gene E. +3 more
openaire +3 more sources
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Golden Eagle Occupancy Surveys and Monitoring Strategy in Coastal Southern California, United States
Frontiers in Ecology and Evolution, 2022 Golden eagles (Aquila chrysaetos) are of increasing conservation concern in western North America. Effective conservation measures for this wide-ranging, federally protected raptor species require monitoring frameworks that accommodate strong inference ...
J. David Wiens +5 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Paired sampling standardizes point count data from humans and acoustic recorders
Avian Conservation and Ecology, 2017 Acoustic recordings are increasingly used to quantify occupancy and abundance in avian monitoring and research. The recent development of relatively inexpensive programmable autonomous recording units (ARUs) has further increased the utility of acoustic ...
Steven L. Van Wilgenburg +3 more
doaj +1 more source