Results 61 to 70 of about 561,010 (268)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
A Novel Sensing Strategy Based on Energy Detector for Spectrum Sensing
Applied Sciences, 2019 Sensing strategy directly influences the sensing accuracy of a spectrum sensing scheme. As a result, the optimization of a sensing strategy appears to be of great significance for accuracy improvement in spectrum sensing.
Hai Huang, Jia Zhu, Junsheng Mu
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Snake diversity, occupancy, and detection on Thailand's largest university campus
Ecology and EvolutionMore than 240 species of snake have been described from Thailand, yet basic natural history and ecology for this group of animals remains scarce in human disturbed environments despite conservation and human medical significance of them in these habitats.
Curt H. Barnes +3 more
doaj +1 more source
Wildlife Society Bulletin, 2011 Estimates regarding population parameters are often based on data from surveys. To ensure that such estimates are as accurate as possible, it is important to know the detectability resulting from the particular survey method used.
Jeanine M. Refsnider +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Electroshocking as a survey technique for stream‐dwelling amphibians
Wildlife Society Bulletin, 2012 Electroshocking has long been employed as a survey technique for fish, but has not been directly tested against rock rolling as a survey methodology for stream‐dwelling amphibians.
John O. Cossel Jr. +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Evaluation of an automated recording device for monitoring forest birds
Wildlife Society Bulletin, 2012 Monitoring of forest songbirds via auditory detections during point surveys can be enhanced by using preprogrammed recording devices. During May–July 2008, we compared boreal forest bird surveys conducted with SM‐1 bird song recorders (Wildlife Acoustics,
Lisa A. Venier +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source