Results 101 to 110 of about 3,117,505 (304)
Frontiers in Public Health, 2017 Genotoxicity and carcinogenicity testing of pharmaceuticals prior to commercialization is requested by regulatory agencies. The bacterial mutagenicity test was considered having the highest accuracy of carcinogenic prediction.
Qianying Liu +7 more
doaj +1 more source
Predicting acute aortic syndrome using aortic dissection detection risk score, D-dimer, and X-ray. [PDF]
Heliyon, 2023 Song DH, Choi JH, Lee JY.
europepmc +1 more source
Outliers in Garch models and the estimation of risk measures [PDF]
In this paper we focus on the impact of additive level outliers on the calculation of risk measures, such as minimum capital risk requirements, and compare four alternatives of reducing these measures' estimation biases. The first three proposals proceed
Aurea Grané, Helena Veiga
core
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Circulating Tumor DNA Profiling for Detection, Risk Stratification, and Classification of Brain Lymphomas. [PDF]
J Clin Oncol, 2023 Mutter JA +26 more
europepmc +1 more source
DETERRENCE OF A CRIMINAL TEAM: HOW TO RELY ON ITS MEMBERS' SHORT COMINGS ? [PDF]
In this paper, we assume that a criminal organization is an agency where the Principal and the Agent have different sensibilities towards the risk of arrestation and punishment, and at the same time have different skills with respect to general ...
Eric LANGLAIS
core
Fungal infections after liver transplantation [PDF]
, 1988 The risk factors for development of invasive fungal infections after liver transplantation were (1) longer duration of treatment with nonprophylactic IV antibiotics, (2) longer cumulative surgical time and a higher number of laparotomies, (3) an ...
Dummer, JS +6 more
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Unique Considerations in Early Detection, Risk, and Awareness of Endometrial Cancer in Black Women. [PDF]
Cancer Control, 2023 Schlumbrecht M, Wright K, George S.
europepmc +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source