Results 121 to 130 of about 1,939,280 (298)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

FEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López, Özge Yilmaz Ardicli, Mübeccel Akdis   +2 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

CATM-CFAR detector in the receiver of the software defined radar [PDF]

Scientific Technical Review, 2014
This paper presents a model of the CATM-CFAR detector in the receiver of the software defined radar. The mentioned detector is named cell-averaging-trimmed-mean CFAR. It is a combination of cell-averaging and trimmed mean CFAR.
Ivković Dejan, Andrić Milenko, Zrnić Bojan, Okiljević Predrag, Kozić Nadica   +4 more
doaj  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Chemical Stability of Metal Halide Perovskite Detectors

Inorganics
Metal halide perovskite (MHP) detectors are highly esteemed for their outstanding photoelectric properties and versatility in applications. However, they are unfortunately prone to degradation, which constitutes a significant barrier to their sustained ...
Bin Zhang, Bin Xue, Shuang Xiao, Xingzhu Wang   +3 more
doaj   +1 more source

Semiconductor Detectors [PDF]

Science, 1966
T, Hall, H R, Bowman, E K, Hyde
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

The AMS-RICH velocity and charge reconstruction

, 2007
The AMS detector, to be installed on the International Space Station, includes a Ring Imaging Cerenkov detector with two different radiators, silica aerogel (n=1.05) and sodium fluoride (n=1.334).
Aguilar-Benitez, M., Arruda, L., Barao, F., Baret, B., Barrau, A., Barreira, G., Belmont, E., Berdugo, J., Borges, J., Buenerd, M., Casadei, D., Casaus, J., Cortina, E., Costado, M., Crespo, D., de la Guia, C., Delgado, C., Derome, L., Diaz, C., Garcia-Lopez, R., Goncalves, P., Herrero, A., Lanciotti, E., Laurenti, G., Malinin, A., Mana, C., Mangin-Brinet, M., Marin, J., Martinez, G., Menchaca-Rocha, A., Palomares, C., Pereira, R., Pimenta, M., Putze, A., Sallaz-Damaz, Y., Seo, E. S., Sevilla, I., Torrento, A., Vargas-Trevino, M., Veziant, O.   +39 more
core   +1 more source