Results 101 to 110 of about 1,072,644 (295)

Dactolisib outperforms Rapamycin in potentiating apoptosis induced by XPO1, Bcl‐2 and Mcl‐1 blockade in preclinical glioblastoma models

FEBS Open Bio, EarlyView.
The PAM pathway and its impact on cellular metabolism. Color‐coded key symbols represent Rapamycin (R, orange, targeting mTOR) and Dactolisib (D, green, targeting PI3K/mTOR), indicating their sites of action. Created with BioRenders.com. Glioblastoma resists therapy through interconnected survival programs.
Kai Zhao, Leonie Meyer, Madita Braun, Katharina Otte, Celine Bitter, Maite Pawlik, Hartmann Raifer, Frederik Helmprobst, Axel Pagenstecher, Hans Urban, Michael C. Burger, Michael W. Ronellenfitsch, Joachim P. Steinbach, Jarmila Jedelská, Shamim Bagheri, Behrooz H. Yousefi, Pietro Di Fazio, Markus Luster, Andreas H. Mahnken, Andreas Neubauer, Andreas Burchert, Christopher Nimsky, Jörg W. Bartsch, Tillmann Rusch   +23 more
wiley   +1 more source

Development and Application of External Moving Type Calibration Device for Beam Detector Based on Quasi-impedance Matching Transmission

Yuanzineng kexue jishu, 2022
The beam calibration results are affected by the impedance of the calibration device. If impedance matching is not maintained, reflected signals would be generated, which would lead to the superposition of reflected signals and excitation signals ...
BAI Haitao;WANG Yi;HE Xiaozhong;LIAO Shuqing;SHI Jinshui
doaj  

Design, calibration, and performance of the MINERvA detector

Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 2014
The MINERvA experiment is designed to perform precision studies of neutrino-nucleus scattering using $ν_μ$ and ${\barν}_μ$ neutrinos incident at 1-20 GeV in the NuMI beam at Fermilab. This article presents a detailed description of the \minerva detector and describes the {\em ex situ} and {\em in situ} techniques employed to characterize the detector ...
Aliaga, L., Bagby, L., Baldin, B., Baumbaugh, A., Bodek, A., Bradford, R., Brooks, W.K., Boehnlein, D., Boyd, S., Budd, H., Butkevich, A., Martinez Caicedo, D.A., Castromonte, C.M., Christy, M.E., Chvojka, J., da Motta, H., Damiani, D.S., Danko, I., Datta, M., DeMaat, R., Devan, J., Draeger, E., Dytman, S.A., Díaz, G.A., Eberly, B., Edmondson, D.A., Felix, J., Fields, L., Fiorentini, G.A., Flight, R.S., Gago, A.M., Gallagher, H., George, C.A., Gielata, J.A., Gingu, C., Gobbi, B., Gran, R., Grange, J., Grossman, N., Harris, D.A., Heaton, J., Higuera, A., Hobbs, J.A., Howley, I.J., Hurtado, K., Jerkins, M., Kafka, T., Kantner, M.O., Keppel, C., Kilmer, J., Kordosky, M., Krajeski, A.H., Kumbartzki, G.J., Lee, H., Leister, A.G., Locke, G., Maggi, G., Maher, E., Manly, S., Mann, W.A., Marshall, C.M., McFarland, K.S., McGivern, C.L., McGowan, A.M., Mislivec, A., Morfín, J.G., Mousseau, J., Naples, D., Nelson, J.K., Niculescu, G., Niculescu, I., O'Connor, C.D., Ochoa, N., Olsen, J., Osmanov, B., Osta, J., Palomino, J.L., Paolone, V., Park, J., Perdue, G.N., Peña, C., Pla-Dalmau, A., Rakotondravohitra, L., Ransome, R.D., Ray, H., Ren, L., Rubinov, P., Rude, C., Sassin, K.E., Schellman, H., Schmitz, D.W., Schneider, R.M., Schulte, E.C., Simon, C., Snider, F.D., Snyder, M.C., Solano Salinas, C.J., Tagg, N., Tice, B.G., Tilden, R.N., Tzanakos, G., Velásquez, J.P., Walton, T., Westerberg, A., Wolcott, J., Wolthuis, B.A., Woodward, N., Wytock, T., Zavala, G., Zeng, H.B., Zhang, D., Zhu, L.Y., Ziemer, B.P.   +112 more
openaire   +2 more sources

Design and evaluation of FEBS Education and Training Academy module – Integrating generative artificial intelligence into life‐science education

FEBS Open Bio, EarlyView.
Life‐science educators from 14 countries redesigned their own course materials with generative AI in a three‐session, pedagogy‐first FEBS Education and Training Academy workshop built on PICRAT. Among 12 matched respondents, four more reported high confidence in each of five practical domains, and 10 of 13 reported implementing at least one idea ...
Zvonimir Mlinarić, Ali Burak Özkaya
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Software timing calibration of the ARGO-YBJ detector

, 2009
The ARGO-YBJ experiment is mainly devoted to search for astronomical gamma sources. The arrival direction of air showers is reconstructed thanks to the times measured by the pixels of the detector. Therefore, the timing calibration of the detector pixels
Di Sciascio G, Rossi E, Sheng XD, Ruggieri F, Yuan AF, Yang QY, Zhang L, Feng ZY, Ferrigno C, James I, Zhang P, Pistilli P, Xue L, Bernardini P, Dai BZ, Feng CF, Zhu FR, Wu CY, Wang YG, Mancarella G, Jia HY, Li HJ, Mastroianni S, Santonico R, Vallania P, Pino C, Yang XC, Branchini P, Piazzoli BD, Zhaxisangzhu, Zhou XX, Danzengluobu, Melcarne AKC, Shen PR, Cheng N, Nicastro L, Panareo M, Yu GC, Galeotti P, Stanescu C, Zhang JL, Liguori G, Zha M, Yang HT, Salvini P, Iacovacci M, Bacci C, Cao Z, Shi F, Saggese L, Zhu QQ, Camarri P, Zizzi G., Perrone L, Wang H, Huang Q, Liberti B, Marsella G, Palummo L, Dattoli M, Labaciren, Wu HR, Creti P, Galeazzi F, Gargana R, Martello D, Bi XJ, BUSSINO, Severino Angelo Maria, Bleve C, Ding XH, Zhang XY, Cappa A, Chen SZ, Budano A, Catalanotti S, Staiti GD, Zhang HM, Bartoli B, Lu H, Di Girolamo T, Liu CQ, Ning CC, Cattaneo C, Celio P, Liu J, He HH, Aielli G, De Vincenzi M, Mu J, Xu B, Cusumano G, Cardarelli R, Gou QB, Surdo A, Meng XR, Vigorito C, Hu HB, MARI, Stefano Maria, Li JY, Qu XB, Tan YH, Segreto A, De Mitri I, Zhang Y, Cui SW, Vernetto S, Cavaliere S, Gao XY   +107 more
core   +2 more sources

Alignment and Calibration of the CMS Detector

, 2011
Fast and efficient methods for the calibration and the alignment of the detector are a key asset to exploit the physics potential of the CMS detector. The CMS experiment has set up a powerful framework for alignment and calibration, which is based on ...
Cerminara, Gianluca
core  

Measurement of the multi-jet cross-sections with the ATLAS detector at the LHC [PDF]

, 2012
Inclusive multi-jet production is studied using the ATLAS detector for proton-proton collisions with a center-of-mass energy of 7 TeV at the Large Hadron Collider at CERN.
ZINONOS, ZINONAS
core  

The ALICE Silicon Pixel Detector Control system and online calibration tools [PDF]

, 2007
The ALICE Silicon Pixel Detector (SPD) contains nearly 107 hybrid pixel cells. The operation of the SPD requires online control and monitoring of some 2000 parameters and » 50000DACs.
Tydesjo, H, Kluge, A, Krivda, M, Riedler, P, Torcato De Matos, C, Caselle, M, Ceresa, S, Cali, I A   +7 more
core   +1 more source

Acute Kidney Injury After Mechanical Thrombectomy for Stroke in Patients With Pre‐Existing Renal Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Acute kidney injury (AKI) is a common but often underrecognized complication in ischemic stroke patients undergoing mechanical thrombectomy, particularly among those with pre‐existing renal impairment. This study evaluated the incidence, risk factors, and clinical impact of AKI in this high‐risk population.
Michał Borończyk, Marcel Pilarek, Emilia Jaworska, Natalia Kardas, Oliwia Barnaś, Julia Woźniak, Iga Machała, Julia Węgrzynek‐Gallina, Joanna Siuda, Anna Hawrot‐Kawecka, Anetta Lasek‐Bal   +10 more
wiley   +1 more source