Results 71 to 80 of about 945,412 (297)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
The Muon Collider is one of the most promising future collider facilities with the potential to reach multi-TeV center-of-mass energy and high luminosity.
Paolo Andreetto +28 more
doaj +1 more source
Hybrid tracking detector based on semiconductor and gas technologies
New Silicon-Gas Pixel Detector (SiGPD) is the result of the further development already proposed Gas-Pixel Detector (GPD). The only disadvantage of GPD was the uncertainty of the particle arriving time.
Bashindzhagyan George +4 more
doaj +1 more source
Charge amplification concepts for direction-sensitive dark matter detectors
Direction measurement of weakly interacting massive particles in time-projection chambers can provide definite evidence of their existence and help to determine their properties. This article demonstrates several concepts for charge amplification in time-
A. Kaboth +40 more
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Discrepancy in tidal deformability of GW170817 between the Advanced LIGO twin detectors
We find that the Hanford and Livingston detectors of Advanced LIGO derive a distinct posterior probability distribution of binary tidal deformability Λ[over ̃] of the first binary-neutron-star merger GW170817.
Tatsuya Narikawa +6 more
doaj +1 more source
Measurements of top quark properties with the ATLAS detector
A selection of recent top quark measurements performed with the ATLAS detector is presented here, with data taken in 2011 and 2012 at centre-of-mass energies of 7 TeV and 8 TeV, respectively. The analyses cover the determination of the top pole mass by a
Unverdorben Christopher
doaj +2 more sources
Magnetic nanoparticles combine unique magnetic properties that can be used in a variety of biomedical applications for therapy and diagnostics. These applications place high demands on the magnetic properties of nanoparticles. Thus, research, development,
Norbert Löwa +8 more
doaj +1 more source
Neutrino Detection using Lead Perchlorate
We discuss the possibility of using lead perchlorate as a neutrino detector. The primary neutrino interactions are given along with some relevant properties of the material.Comment: 2 pages, 2 figures, TAUP-99, TEX ...
Armbruster +9 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

