Results 91 to 100 of about 9,359 (237)

Continuous subcutaneous insulin infusion therapy and multiple daily insulin injections in type 1 diabetes mellitus: a comparative overview and future horizons. [PDF]

open access: yes, 2015
INTRODUCTION: Continuous subcutaneous insulin infusion (CSII) therapy is currently accepted as a treatment strategy for type 1 diabetes. Transition from multiple daily injection therapy (MDI; including basal-bolus regimens) to CSII is based on ...
Hovorka, R, Mohd-Thabit, HA
core   +1 more source

Nanomedicines Against Mitochondrial Dysfunction‐Induced Metabolic Diseases

open access: yesAdvanced Science, Volume 12, Issue 48, December 29, 2025.
Mitochondrial dysfunction is central to metabolic diseases. Nanomedicine offers transformative approaches for restoring function via targeted delivery, responsive release, and multimodal therapy. This review outlines the pathological basis, nanocarrier design, organelle‐specific targeting, recent advances, and future clinical translation challenges ...
Ke Xu   +9 more
wiley   +1 more source

Characteristics Relating to Adherence and Persistence to Basal Insulin Regimens Among Elderly Insulin-Naïve Patients with Type 2 Diabetes: Pre-Filled Pens versus Vials/Syringes [PDF]

open access: yes, 2015
INTRODUCTION: Previous studies have found higher rates of adherence in patients with type 2 diabetes mellitus (T2DM) using insulin pens compared to vial and syringe administration; however, little evidence is available to support this observation in ...
D. Chad Moretz   +5 more
core   +1 more source

Understanding the Increasing Prevalence of Obesity in Patients With Type 1 Diabetes: Strategies for Improving Clinical Care

open access: yesObesity, Volume 33, Issue 12, Page 2246-2263, December 2025.
ABSTRACT The presence of excess weight is no longer a distinguishing feature between patients with type 1 diabetes (T1D) and those with type 2 diabetes (T2D). Obesity treatment in patients with T2D improves glycemic control and reduces or even eliminates medication burden.
Kathleen R. Ruddiman   +2 more
wiley   +1 more source

Brazilian Diabetes Society consensus statement: intensive insulin therapy and insulin pump therapy [PDF]

open access: yes, 2006
This article reports the Brazilian Diabetes Society consensus statement on intensive insulin therapy and insulin pump therapy, arrived at during an update symposium held in 2003 for this specific purpose.
Chacra, Antonio Roberto   +6 more
core   +4 more sources

Declining incidence of hypoglycaemia in diabetes secondary to chronic pancreatitis: A nationwide cohort study from 2003 to 2022

open access: yesDiabetes, Obesity and Metabolism, Volume 27, Issue 12, Page 7075-7084, December 2025.
Abstract Aims Population‐based studies have consistently shown that individuals with diabetes secondary to chronic pancreatitis (pancreatic diabetes) have a high risk of hypoglycaemia. We aimed to investigate whether this risk has declined over recent years following the introduction of modern glucose‐lowering medications. Materials and Methods In this
Line Davidsen   +5 more
wiley   +1 more source

Tolerability, safety and adherence to treatment with insulin detemir injection in the treatment of type 2 diabetes

open access: yesPatient Preference and Adherence, 2008
Athena Philis-TsimikasScripps Whittier Diabetes Institute, La Jolla, CA, USAAbstract: The progressive nature of type 2 diabetes poses challenges in the clinic: treatment must be continually reviewed and adjusted in response to the patient’s ...
Athena Philis-Tsimikas
doaj  

Cost-Effectiveness of Insulin Glargine and Insulin Detemir in the Basal Regimen for Naïve Insulin Patients with Type 2 Diabetes Mellitus (T2DM) in Malaysia

open access: yesClinicoEconomics and Outcomes Research, 2020
Asrul Akmal Shafie,1 Chin Hui Ng2 1Discipline of Social and Administrative Pharmacy, School of Pharmaceutical Sciences, Penang, Malaysia; 2Pharmacy Department, Hospital Raja Permaisuri Bainun, Ipoh 30450, Perak, MalaysiaCorrespondence: Asrul Akmal ...
Shafie AA, Ng CH
doaj  

Efficacy and safety of insulin lispro protamine suspension as basal supplementation in patients with type 2 diabetes

open access: yesTherapeutic Advances in Endocrinology and Metabolism, 2012
The three currently marketed long-acting insulin analogs, glargine, detemir and insulin lispro protamine suspension (ILPS), represent the most significant advances in basal insulin supplementation since the 1940s and 1950s and the introduction of the ...
Dario Giugliano, Katherine Esposito
doaj   +1 more source

Detemir potential applications in the treatment of diabetes during pregnancy: proven benefits and perspectives

open access: yesСахарный диабет, 2016
In recent years there is notable growing prevalence of gestational and overt diabetes in pregnant women while rate of obstetric complications, neonatal morbidity, perinatal mortality in women with diabetes is maintained at the high level as compared with
Lyudmila A. Ruyatkina, Maksim Y. Sorokin
doaj   +1 more source

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