Results 21 to 30 of about 4,485 (161)
Basal insulin titration algorithms in patients with type 2 diabetes: the simplest is the best (?)
Mìžnarodnij Endokrinologìčnij Žurnal, 2023 Basal insulin is the first and main component of insulin therapy in patients with type 2 diabetes mellitus (T2DM). Based on the shortcomings of human NPH insulin and the advantages provided by long-acting basal insulin analogues, they are recommended ...
V.I. Katerenchuk
doaj +1 more source
Detemir dan Glargine: Profil Keamanan, Efikasi dan Farmakoekonomi Insulin Long-acting [PDF]
, 2021 Diabetes melitus merupakan sebuah penyakit gangguan metabolik yang ditandai dengan adanya peningkatan kadar gula darah karena tubuh tidak dapat memproduksi insulin dengan efektif, sehingga diperlukan insulin buatan untuk mengontrol kadar gula darah ...
Sari, Nuraini Maulidina +2 more
core +1 more source
Effects of insulin and analogues on carcinogen-induced mammary tumours in high-fat-fed rats
Endocrine Connections, 2018 It is not fully clarified whether insulin glargine, an analogue with a high affinity for insulin-like growth factor-1 receptor (IGF-1R), increases the risk for cancers that abundantly express IGF-1R such as breast cancer or some types of breast cancer ...
Yusaku Mori +8 more
doaj +1 more source
Journal of Diabetology, 2022 Aims and Objectives: Despite the advantages offered by current basal analogs, the management of type 1 diabetes (T1D) in children and adolescents is a great challenge till now.
Bedowra Zabeen +5 more
doaj +1 more source
Prevalence of pharamcologically-treated diabetes in term pregnancies in Haryana, India
Indian Journal of Endocrinology and Metabolism, 2017 Gestational diabetes mellitus (GDM) is common in pregnancy. Epidemiological studies have described the prevalence of GDM in the antenatal period, but do not assess the number of women who require pharmacological therapy at term.
Bharti Kalra +3 more
doaj +1 more source
Modern basal insulin analogs: An incomplete story
Indian Journal of Endocrinology and Metabolism, 2014 The currently available basal insulin does not completely mimic the endogenous insulin secretion. This has continued to promote the search for ideal basal insulin.
Awadhesh Kumar Singh +1 more
doaj +1 more source
Diabetology & Metabolic Syndrome, 2017 Background Type II diabetes is an important health problem with a complex connection to obesity, leading to a broad range of cardiovascular complications.
Tomislav Bozek +8 more
doaj +1 more source
A subcutaneous insulin pharmacokinetic model for insulin Detemir [PDF]
, 2020 Background and Objective: Type 2 diabetes (T2D) is rapidly increasing in incidence and has significant social and economic costs. Given the increasing cost of complications, even relatively short delays in the onset of T2D can significantly reduce long ...
Knopp JL, Chase, Geoff, van Noorden B
core +1 more source
Flying under the radar: treatment of refractory hyperglycemia
Endocrinology, Diabetes & Metabolism Case Reports, 2016 Clinicians are often presented with the scenario of what to do when one medication in a drug class has failed a therapeutic trial on a patient. We encountered a patient who developed profound resistance to glargine, aspart and regular insulin, but had a ...
S M Kandel, J A Cosgriff
doaj +1 more source
The Crosstalk Between Diabetes and Alzheimer's Disease: A Molecular Perspective
Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 4, October 2026.Increasing evidence indicates an association between type 2 diabetes mellitus and Alzheimer’s disease, contributing to the proposed concept of AD as “type 3 diabetes.” Shared biological features such as impaired insulin signaling, chronic inflammation, mitochondrial dysfunction, and oxidative stress have been observed in both T2DM and AD.
Deniz Catakli +3 more
wiley +1 more source