Results 31 to 40 of about 9,359 (237)

Cost-Effectiveness Analysis of Insulin Detemir Compared to Neutral Protamine Hagedorn (NPH) in Patients with Type 1 and Type 2 Diabetes Mellitus in Spain [PDF]

, 2015
Introduction: An Excel® (Microsoft Corporation) model was adapted to estimate the short-term (1-year) cost effectiveness of insulin detemir (IDet) versus neutral protamine Hagedorn (NPH) insulin in patients initiating insulin treatment with type 1 ...
A Philis-Tsimikas, AE Pontiroli, AJ Lee, AJ Palmer, American Diabet es Association, BM Frier, D Orozco-Beltrán, ER Seaquist, F Alvarez Guisasola, J Smith-Palmer, JA Sacristán, K Eeg-Olofsson, K Hermansen, LF Meneghini, M Brod, M Evans, M Hammer, M Monami, M Ridderstråle, MH Gschwend, PC Bartley, PE Cryer, PE Cryer, SA Williams, SE Inzucchi, UK Hypoglycaemia Study Group, WJ Valentine, WJ Valentine, WJ Valentine   +28 more
core   +2 more sources

Glycemic control and long-acting insulin analog utilization in patients with type 2 diabetes [PDF]

, 2010
Introduction: The objective was to compare glycemic control, insulin utilization, and body weight in patients with type 2 diabetes (T2D) initiated on insulin detemir (IDet) or insulin glargine (IGlar) in a real-life setting in the Netherlands.
A. Dornhorst, A. Patel, A. Philis-Tsimikas, A. Rubino, A.B. King, American Diabetes Association., B.J. Borah, D.M. Nathan, Edith M. Heintjes, Fernie J. A. Penning-van Beest, G. Goodall, G. Rutten, G.E.H.M. Rutten, J.B. Brown, J.B. Marks, K. Hermansen, L. Czupryniak, L. Meneghini, L.F. Meneghini, L.F. Meneghini, M. Monami, M. Yenigun, M.J. Calvert, M.P. Herk-Sukel van, O. Pedersen, O.E. Johansen, P. Fontaine, P. Gaede, P. Hollander, P. Raskin, P. Rossetti, R.M.C. Herings, R.M.C. Herings, R.R. Holman, Ron M. C. Herings, S. Mudaliar, S.A. Brunton, S.E. Nelson, S.I. McFarlane, T. Haak, Torsten E. Christensen, Trine L. Thomsen, UK Prospective Diabetes Study, W. Fakhoury   +43 more
core   +1 more source

Insulin analogues dosing and costs - comparing real-life daily doses of insulin detemir and insulin glargine in type 2 diabetes patients

BMC Endocrine Disorders, 2012
Background The uncertainties regarding dose similarities between basal long-acting insulin analogues remain. Recent real-world studies indicate dose similarities between insulin detemir and insulin glargine, but further studies are still warranted.
Jakobsen Marie, Dalsgaard Mette, Hørmann Morten, Møller Daniél   +3 more
doaj   +1 more source

Glycaemic control and prevalence of hypoglycaemic events in children and adolescents with type 1 diabetes mellitus treated with insulin analogues [PDF]

, 2014
Background/Aim. An ideal insulin regimen for children and adolescents with type 1 diabetes mellitus (T1DM) should be physiological, flexibile and predictable, protecting against hypoglycaemia.
Milenković Tatjana, Mitrović Katarina, Plavšić Ljiljana, Todorović Slađana, Vuković Rade, Zdravković Dragan   +5 more
core   +1 more source

The influence of dopamine-beta-hydroxylase and catechol O-methyltransferase gene polymorphism on the efficacy of insulin detemir therapy in patients with type 2 diabetes mellitus

Diabetology & Metabolic Syndrome, 2017
Background Type II diabetes is an important health problem with a complex connection to obesity, leading to a broad range of cardiovascular complications.
Tomislav Bozek, Antonela Blazekovic, Matea Nikolac Perkovic, Kristina Gotovac Jercic, Aleksandra Sustar, Lea Smircic-Duvnjak, Tiago F. Outeiro, Nela Pivac, Fran Borovecki   +8 more
doaj   +1 more source

Basal insulin titration algorithms in patients with type 2 diabetes: the simplest is the best (?)

Mìžnarodnij Endokrinologìčnij Žurnal, 2023
Basal insulin is the first and main component of insulin therapy in patients with type 2 diabetes mellitus (T2DM). Based on the shortcomings of human NPH insulin and the advantages provi­ded by long-acting basal insulin analogues, they are recommended ...
V.I. Katerenchuk
doaj   +1 more source

Comparing the efficacy and safety of insulin detemir versus neutral protamine hagedorn insulin in treatment of diabetes during pregnancy: a randomized, controlled study

BMJ Open Diabetes Research & Care, 2020
Objective To compare the efficacy and safety of insulin detemir (IDet) versus neutral protamine Hagedorn (NPH) insulin used in pregnant women with diabetes.
Jing Ji, Zhangya He, Zhao Yang, Y. Mi, Nanjing Guo, Hong Zhao, Jiayi Gao, Zhengfeei Ma, Xiaoqin Luo, Zhen Han   +9 more
semanticscholar   +1 more source

Comparison of efficacy of detemir and degludec insulin in the management of children and adolescents with type 1 diabetes

Journal of Diabetology, 2022
Aims and Objectives: Despite the advantages offered by current basal analogs, the management of type 1 diabetes (T1D) in children and adolescents is a great challenge till now.
Bedowra Zabeen, Bulbul Ahmed, Nasreen Islam, Samin Tayyeb, Jebun Nahar, Kishwar Azad   +5 more
doaj   +1 more source

Glucose-responsive insulin activity by covalent modification with aliphatic phenylboronic acid conjugates [PDF]

, 2014
Since its discovery and isolation, exogenous insulin has dramatically changed the outlook for patients with diabetes. However, even when patients strictly follow an insulin regimen, serious complications can result as patients experience both ...
Anderson, Daniel Griffith, Chou, Danny Hung-Chieh, Cortinas, Abel Bryan, Deng, David, Langer, Robert S, Lin, Amy B., Tang, Benjamin C., Thapa, Lavanya S., Truong, Jonathan V., Webber, Matthew   +9 more
core   +1 more source

Effects of insulin and analogues on carcinogen-induced mammary tumours in high-fat-fed rats

Endocrine Connections, 2018
It is not fully clarified whether insulin glargine, an analogue with a high affinity for insulin-like growth factor-1 receptor (IGF-1R), increases the risk for cancers that abundantly express IGF-1R such as breast cancer or some types of breast cancer ...
Yusaku Mori, Eunhyoung Ko, Rudolf Furrer, Linda C Qu, Stuart C Wiber, I George Fantus, Mario Thevis, Alan Medline, Adria Giacca   +8 more
doaj   +1 more source