Results 41 to 50 of about 9,359 (237)

A Single Center, Open-Labeled Trial To Investigate The Pharmacokinetics of Insulin Detemir in Healthy Taiwanese Subjects

open access: yes, 2021
Backgrounds: Insulin detemir(nn304) is a long-acting insulin analogue reported to provide more predictable blood glucose level throughout the day, leading to a lower within-subject variability compared to NPH insulin.
C. Kwok, L. Ho
semanticscholar   +1 more source

Prevalence of pharamcologically-treated diabetes in term pregnancies in Haryana, India

open access: yesIndian Journal of Endocrinology and Metabolism, 2017
Gestational diabetes mellitus (GDM) is common in pregnancy. Epidemiological studies have described the prevalence of GDM in the antenatal period, but do not assess the number of women who require pharmacological therapy at term.
Bharti Kalra   +3 more
doaj   +1 more source

Interaction of β-amyloid Peptide with Insulin Detemir Studied by Biolayer Interferometry and Molecular Modelling

open access: yesJournal Biomed
The study of β-amyloid peptide (Aβ) interactions with protein and peptide ligands is a relevant research task. Aβ complexes with drugs that are considered as promising candidates for the therapy of Alzheimer’s disease are of particular interest.
M. Shevelyova   +5 more
semanticscholar   +1 more source

Managing feline diabetes: current perspectives [PDF]

open access: yes, 2018
Diabetes mellitus is a common endocrine disease in cats. While type 2 diabetes is the most common form seen in cats, other underlying causes may contribute to insulin resistance.
Gottlieb, Susan, Rand, Jacquie
core   +1 more source

Modern basal insulin analogs: An incomplete story

open access: yesIndian Journal of Endocrinology and Metabolism, 2014
The currently available basal insulin does not completely mimic the endogenous insulin secretion. This has continued to promote the search for ideal basal insulin.
Awadhesh Kumar Singh   +1 more
doaj   +1 more source

Similar Breast Cancer Risk in Women Older Than 65 Years Initiating Glargine, Detemir, and NPH Insulins

open access: yesDiabetes Care, 2020
OBJECTIVE To assess whether initiation of insulin glargine (glargine), compared with initiation of NPH or insulin detemir (detemir), was associated with an increased risk of breast cancer in women with diabetes.
M. Bradley   +10 more
semanticscholar   +1 more source

Insulin therapy DE‐intensificAtion with iGlarLixi: A phase 4, open‐label, parallel‐group randomised controlled trial

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims To evaluate the efficacy and safety of transitioning from multiple daily injections (MDIs) insulin regimen to once‐daily, fixed‐ratio combination of basal insulin analog glargine 100 U/mL and a glucagon‐like peptide 1 receptor agonist lixisenatide (iGlarLixi) in people with type 2 diabetes (PwT2D). Materials and Methods Insulin therapy DE‐
Peter Novodvorský   +14 more
wiley   +1 more source

Flying under the radar: treatment of refractory hyperglycemia

open access: yesEndocrinology, Diabetes & Metabolism Case Reports, 2016
Clinicians are often presented with the scenario of what to do when one medication in a drug class has failed a therapeutic trial on a patient. We encountered a patient who developed profound resistance to glargine, aspart and regular insulin, but had a ...
S M Kandel, J A Cosgriff
doaj   +1 more source

Injection‐site and dermatologic reactions associated with glucagon‐like peptide‐1 receptor agonists: Insights from meta‐analysis of randomised controlled trials and real‐world evidence

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) are widely used for type 2 diabetes mellitus and obesity, with once‐weekly dosing that supports adherence. However, injection‐site reactions (ISRs) and dermatologic events have been recognised, ranging from mild local events to rare systemic hypersensitivity reactions that may cause ...
Shifa Taj   +6 more
wiley   +1 more source

Critical appraisal of the safety and efficacy of insulin detemir in glycemic control and cardiovascular risk management in diabetics

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2010
Jean-Pierre Le FlochDepartment of Diabetology, Medical Clinic, Villecresnes, FranceAbstract: Insulin detemir is an analog of human insulin designed to provide a long duration of basal insulin action.
Jean-Pierre Le Floch
doaj   +2 more sources

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