Molecular characterisation of long-acting insulin analogues in comparison with human insulin, IGF-1 and insulin X10. [PDF]
PLoS ONE, 2012 AIMS/HYPOTHESIS: There is controversy with respect to molecular characteristics of insulin analogues. We report a series of experiments forming a comprehensive characterisation of the long acting insulin analogues, glargine and detemir, in comparison ...
Bo F Hansen +6 more
doaj +1 more source
Optimizing adipogenic transdifferentiation of bovine mesenchymal stem cells: a prominent role of ascorbic acid in FABP4 induction [PDF]
, 2020 Adipocyte differentiation of bovine adipose-derived stem cells (ASC) was induced by foetal bovine serum (FBS), biotin, pantothenic acid, insulin, rosiglitazone, dexamethasone and 3-isobutyl-1-methylxanthine, followed by incubation in different media to ...
Aschenbach, Jörg R. +6 more
core +1 more source
Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 228-240, January 2026.Data science approaches have been increasingly implemented in healthcare big data to evaluate the safety and effectiveness of drugs. Association discovery is a data mining approach that finds potentially associated elements in high‐dimensional data. We present a novel implementation of the association discovery approach in longitudinal healthcare data ...
George S. Q. Tan +6 more
wiley +1 more source
Projected long-term outcomes in patients with type 1 diabetes treated with fast-acting insulin aspart versus conventional insulin aspart in the UK setting [PDF]
, 2017 Aims: Many patients with type 1 diabetes mellitus (T1DM) fail to achieve optimal glycemic control and mealtime insulins that more closely match physiological insulin secretion can help improve treatment.
Buchs, S. +5 more
core +1 more source
A Rational Approach to Pharmacotherapy in Pregnancy
The Journal of Clinical Pharmacology, Volume 66, Issue 1, January 2026.Abstract Most pregnant individuals are exposed to at least one medication, whether prescription or over the counter, during pregnancy. Despite the ubiquity of medication use in pregnancy, there remains no standardized framework to guide clinicians in selecting the most appropriate pharmacotherapy that balances maternal needs with fetal safety. This gap
Gregory W. Kirschen +2 more
wiley +1 more source
Economic analysis of Lixisenatide in Diabetes Mellitus Type 2
Качественная клиническая практика, 2018 Usage of glucagon like peptide-1 receptors’ agonists (aGLP-1) is a new step in the treatment of Diabetes Mellitus Type 2 (DM 2). General attractive effects are positive effect on bodyweight, lower risk of hypoglycemia, compliance and possibility of ...
A. S. Kolbin +5 more
doaj
Cerebrocortical beta activity in overweight humans responds to insulin detemir.
PLoS ONE, 2007 BackgroundInsulin stimulates cerebrocortical beta and theta activity in lean humans. This effect is reduced in obese individuals indicating cerebrocortical insulin resistance.
Otto Tschritter +9 more
doaj +1 more source
Analisis Efektivitas Biaya Penggunaan Terapi Kombinasi Insulin dan Oho pada Pasien Diabetes Melitus Tipe 2 Rawat Jalan di RSUD Wangaya [PDF]
, 2013 Bervariasinya penggunaan terapi insulin tunggal atau kombinasi insulin dengan Obat Hipoglikemik Oral (OHO) pada pasien DM tipe 2 dengan kontrol glukosa darah yang belum adekuat akan mengakibatkan adanya perbedaan dalam biaya dan efektivitas terapinya ...
Febryana L, Luh Putu +2 more
core
Euglycemic Diabetic Ketoacidosis in Concurrent Very Low-carbohydrate Diet and Sodium-glucose Transporter-2 Inhibitor Use: A Case Report [PDF]
, 2020 Introduction: With the incredibly high incidence of Type 2 Diabetes in the current population of emergency department patients, it is critical for clinicians to understand the possible complications of the treatment of this disease.
Ault, Brian +2 more
core
Very tight vs. tight control: what should be the criteria for pharmacologic therapy dose adjustment in diabetes in pregnancy? Evidence from randomized controlled trials [PDF]
, 2017 INTRODUCTION: There is inconclusive evidence from randomized controlled trials (RCTs) to support any specific criteria for pharmacologic therapy dose adjustment in diabetes in pregnancy.
Berghella, Vincenzo +3 more
core +1 more source