Results 51 to 60 of about 256,768 (386)

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

Hydrophobic interaction chromatography [PDF]

, 2011
Most proteins and large polypeptides have hydrophobic regions at their surface. These hydrophobic ‘patches’ are due to the presence of the side chains of hydrophobic or non-polar amino acids such as phenylalanine, tryptophan, alanine and methionine ...
Cummins, Phil, O'Connor, Brendan
core   +1 more source

How Do Short Chain Nonionic Detergents Destabilize G-Protein-Coupled Receptors?

Journal of the American Chemical Society, 2016
Stability of detergent-solubilized G-protein-coupled receptors (GPCRs) is crucial for their purification in a biologically relevant state, and it is well-known that short chain detergents such as octylglucoside are more denaturing than long chain ...
Sangbae Lee, Allen Mao, Supriyo Bhattacharya, N. Robertson, R. Grisshammer, C. Tate, N. Vaidehi   +6 more
semanticscholar   +1 more source

Mesenchymal Stem Cells‐Derived Extracellular Vesicles Mimetics as Osteoinductive Mediators for Bone Healing

Advanced Functional Materials, EarlyView.
Mesenchymal stem cell‐derived nanoghosts (MSC‐NGs) mimic naturally secreted extracellular vesicles (MSC‐EVs) in structure and physicochemical properties but can be synthesized at more translatable yields. As osteogenic agents, MSC‐NGs demonstrate superior outcomes compared to MSC‐EVs.
Antoine Karoichan, Ling Li, Celine J. Agnes, Bettina M. Willie, Maryam Tabrizian   +4 more
wiley   +1 more source

An approach for prioritizing “down-the-drain” chemicals used in the household [PDF]

, 2015
This article has been made available through the Brunel Open Access Publishing Fund.Many chemicals are present in cleaning and personal care products, which after use are washed down the drain and find their way into water bodies, where they may impact ...
Basin, Bolek, Eriksson, Janna, Johnson, Loretz, Loretz, Loretz, Marina Rotsidou, Mark Scrimshaw, Trenholm   +10 more
core   +2 more sources

Ultra‐Effective Light‐Activated Antibacterial Activity via Carboxyl Functionalized Graphene Quantum Dots and Films

Advanced Functional Materials, EarlyView.
Carboxyl‐functionalized graphene quantum dots (cGQDs) exhibit high singlet oxygen quantum yield due to strong spin–orbit coupling. cGQDs achieve minimum bactericidal concentration of only 0.4 µg mL−1 against S. aureus under low‐intensity illumination.
Muhammad Hassnain, Laure S. van Hofwegen, Humeyra Nur Kaleli, Temirlan Kubanaliev, Zafer Eroglu, Asim Onal, Payal P. S. Balraadjsing, Onder Metin, Fahri Alkan, Sebastian A. J. Zaat, Sedat Nizamoglu   +10 more
wiley   +1 more source

Folding factors and partners for the intrinsically disordered protein Micro-Exon Gene 14 (MEG-14) [PDF]

, 2013
The micro-exon genes (MEG) of Schistosoma mansoni, a parasite responsible for the second most widely spread tropical disease, code for small secreted proteins with sequences unique to the Schistosoma genera.
Almeida, Ana Paula U. Araujo, B.A. Wallace, Berriman, Buchan, Cammers-Goodwin, Campen, Catanzano, Chakrabortee, Debora Orcia, DeMarco, Dosztányi, Dunker, Emery, Garnier, Gasteiger, Gryseels, Hsu, Ikeda, Jose Luiz S. Lopes, Kolaskar, Krogh, Lees, Linding, Lopes, Luo, Meersman, Miles, Oldfield, Petersen, Prilusky, Radivojac, Ricardo DeMarco, Smith, Sreerama, Tompa, Uversky, Uversky, Uversky, Uversky, Uversky, Uversky, van Stokkum, Vullo, Wallace, Weinreb, Whitmore, Wien, Yang   +48 more
core   +1 more source

Cell Membrane Vesicle Camouflaged Artificial Cells

Advanced Functional Materials, EarlyView.
Artificial cells camouflaged with a cell membrane vesicle coating are able to assemble into synthetic aggregates that exhibit rudimentary communication capabilities. Additionally, when these artificial cells are equipped with antioxidant capabilities, they are able to protect the intracellular homeostasis in HepG2 cells present in semi‐synthetic ...
Paula De Dios Andres, Stefan Pendlmayr, Noga Gal, Cathrine Abild Meyer, Cecilie Ryberg, Olav Vestrheim, Noel Angelo Kalacas, Fatih Demir, Markus M. Rinschen, Karsten Haupt, Rajeshwar Prosad Mookerjee, Brigitte Städler   +11 more
wiley   +1 more source

Biodegradation of sodium lauryl ether sulfate (SLES) contamination by Pseudomonas aeruginosa isolates

Journal of Degraded and Mining Lands Management
Sodium lauryl ether sulfate (SLES) is a surfactant commonly used in the formulation of detergents, which is typically disposed of in wastewater treatment plants.
Hussein Ali Awadh AL-Zamili, Ithar Kamil Al-Mayaly   +1 more
doaj   +1 more source

ASPECTS CONCERNING THE IDENTIFICATION AND ASSESSMENT OF PROFESSIONAL RISKS IN THE PRODUCTION OF DETERGENTS [PDF]

Fiabilitate şi Durabilitate, 2020
This conference paper present some specific aspects of the input data in the process of identifying and risks assessments related to OH&S (Occupational Health & Safety) for the prevention of injury and/or ill health.
Eugenia BULBOACĂ, Costinel BULBOACĂ, Oana-Roxana CHIVU, Alin Ion ȚĂPÎRDEA, Vergilică T. HARALAMBIE   +4 more
doaj