Results 51 to 60 of about 72,340 (306)

Unraveling the Heterogeneity of Cargo Distribution in the Exogenous Association of Proteins With Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
We characterized the distribution of cargo proteins associated with extracellular vesicles using various exogenous loading methods. In all cases, single‐particle analysis revealed that the distribution of protein content per EV is heterogeneous, following an exponential decay function.
Karl Normak, Marcell Papp, Carolina Paganini, Andrea Zendrini, Paolo Bergese, Dorothea Pinotsi, Paolo Arosio   +6 more
wiley   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

Decellularized Extracellular Matrix Scaffolds to Engineer the Dormant Landscape of Microscopic Colorectal Cancer Liver Metastasis

Advanced Healthcare Materials, EarlyView.
Decellularized liver extracellular matrix scaffolds provide a platform to study dormant liver‐metastatic colorectal cancer. They induce reversible dormancy, in combination with nutrient depletion and low dose chemotherapy, through cell cycle arrest and chemotherapy resistance.
Sabrina N. VandenHeuvel, Lucia L. Nash, Abigail J. Clevenger, Claudia A. Collier, Oscar R. Benavides, Sanjana Roy, Brinlee Goggans, Aelita Salikhova, Anvitha Tharakesh, Svasti Haricharan, Amber N. Stratman, Scott Kopetz, Alex J. Walsh, Shreya A. Raghavan   +13 more
wiley   +1 more source

Increased Anti‐Psoriatic Effect of Anti‐Inflammatory Dendrimers Using Fluid Catanionic Vesicle‐Based Topical Formulations

Advanced Healthcare Materials, EarlyView.
Next‐Generation Psoriasis Therapy – With advanced dendrimer‐based formulations, this study paves the way for highly effective, skin‐permeable treatments. Encapsulated in fluid catanionic vesicles, IMD‐006 and its analogues show promising anti‐psoriatic effects offering a targeted, non‐invasive approach to managing chronic skin inflammation.
Ranime Jebbawi, Abdelouahd Oukhrib, Emily Clement, Hélène Labie, Stéphanie Cassel, Séverine Fruchon, Anne‐Marie Caminade, Michel Simon, Rémy Poupot, Cédric‐Olivier Turrin, Muriel Blanzat   +10 more
wiley   +1 more source

Plasma‐Polymerized Nanoparticles Presenting Fibrillin‐1 Drive Rapid Re‐Endothelialization of Vascular Grafts

Advanced Healthcare Materials, EarlyView.
Commercial vascular grafts are made from ePTFE, a highly hydrophobic, foreign material that fails at a high rate in small‐diameter applications. Plasma polymer nanoparticles (PPN) are a versatile material functionalisation tool, used here to present fibrillin‐1 fragment PF8 on the graft surface.
Bob S. L. Lee, Yuen Ting Lam, Alex H. P. Chan, Praveesuda L. Michael, Timothy C. Mitchell, Jui Chien Hung, Miguel Santos, Khoon S. Lim, Richard P. Tan, Steven G. Wise   +9 more
wiley   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Energy‐Efficient, Sustainable Cascade Glucose Electrooxidation into Glucaric Acid

Advanced Materials, EarlyView.
This study presents a tandem system that efficiently converts glucose into glucaric acid while generating renewable electricity. By decoupling the oxidation process into two cascaded steps, the system achieves an overall 90% Faradaic efficiency and 80% conversion efficiency at ∼0.6 VRHE, significantly reducing energy consumption compared to traditional
Mingming He, Chao Huang, Mingzi Sun, Ruixuan Wang, Yun Song, Jianjun Su, Weihua Guo, Yinger Xin, Qiang Zhang, Yong Liu, Geng Li, Zihao Li, Rui Xue, Bolong Huang, Ben Zhong Tang, Ruquan Ye   +15 more
wiley   +1 more source

Fatty Amines in Detergents and Cosmetics: Current State and Biocircular Perspectives

Cosmetics
Fatty amines are nitrogen-containing organic compounds synthesized from fatty acids, olefins, or alcohols, typically derived from natural oils or petrochemical sources.
Maria-Beatrice Coltelli, Annabel Serpico, Rosa Domenech, Mar Tronch, Carolina Galli, Paolo Sonzini, Clara Escrivà-Cerdán, Sergio Mastroianni, Andrea Lazzeri, Domenico Licursi, Anna Maria Raspolli Galletti   +10 more
doaj   +1 more source

NON-SPECIFIC METHODS FOR DETECTING RESIDUES OF CLEANING AGENTS DURING CLEANING VALIDATION [PDF]

Chemical Industry and Chemical Engineering Quarterly, 2011
Cleaning validation procedures are carried out in order to assure that residues of cleaning agents are within acceptable limits after the cleaning process.
DRAGAN M. MILENOVIĆ, DRAGAN S. PEŠIĆ, SNEŽANA S. MITIĆ   +2 more
doaj  

Purifying natively folded proteins from inclusion bodies using sarkosyl, Triton X-100, and CHAPS

BioTechniques, 2010
We describe a rapid, simple, and efficient method for recovering glutathione S-transferase (GST)- and His6-tagged maltose binding protein (MBP) fusion proteins from inclusion bodies.
Hu Tao, Wenjun Liu, Brandi N. Simmons, Helen K. Harris, Timothy C. Cox, Michael A. Massiah   +5 more
doaj   +1 more source