Results 101 to 110 of about 1,997,664 (317)
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
This paper presents a generalization of the cross product to N dimensions, extending the classical operation beyond its traditional confines in three-dimensional space.
Samir Brahim Belhaouari +6 more
doaj +1 more source
Multiple gcd-closed sets and determinants of matrices associated with arithmetic functions
Let f be an arithmetic function and S= {x1, …, xn} be a set of n distinct positive integers. By (f(xi, xj)) (resp. (f[xi, xj])) we denote the n × n matrix having f evaluated at the greatest common divisor (xi, xj) (resp. the least common multiple [xi, xj]
Hong Siao, Hu Shuangnian, Hong Shaofang
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Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source
On Factorization and Calculation of Determinant of Block Matrices with Triangular Submatrices
In this paper, we consider some block matrices of dimension $nm\times{nm}$ whose components are triangular matrices of dimension $n\times{n}$. We prove that the determinant of such block matrices is determined only by the diagonal elements of their ...
Fatma Altun, Ufuk Kaya
doaj +1 more source
Determinants and Inverses of Ppoeplitz and Ppankel matrices
In this paper, we consider two kinds of special matrices, which are called Ppoeplitz matrix and Ppankel matrix. The idea of matrix transformation is used to compute the determinants and inverses of the Ppoeplitz matrix and the Ppankel matrix.
Zuo Baishuai, Jiang Zhaolin, Fu Deqian
doaj +1 more source
THE EMOTIONAL WELL-BEING OF LEARNERS AS A DETERMINANT OF THE TRAINING ACTIVITY [PDF]
Our article focuses on the complex issue of creating the emotional well-being needed by the students in academic learning. Especially after the COVID-19 pandemic, this challenge has become an aspect that is better acknowledged by both the trainers and
Ecaterina Sarah FRĂSINEANU, Vali ILIE
doaj +1 more source
Contributions to the History of Determinants, 1900–1920 [PDF]
A. C. A.
openalex +1 more source
The authors give a brief review of papers relating to Smith's determinant [cf. \textit{H. J. S. Smith}, Proc. Lond. Math. Soc. 7, 208--212 (1876; JFM 08.0074.02)] and point out a common structure that can be found in many extensions and analogues of Smith's determinant. The common structure is presented in the language of posets.
Pentti Haukkanen +2 more
openaire +2 more sources

