Results 121 to 130 of about 708,846 (313)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Generalized matrix functions, determinant and permanent
پژوهشهای ریاضی, 2022 Introduction Since linear and multilinear algebra has many applications in different branches of sciences, the attention of many mathematicians has been attracted to it in recent decades. The determinant and the permanent are the most important functions
Mohammad Hossein Jafari, Ali Reza Madadi
doaj
, 2015 dASbACH等人给出了链环行列式的一个交错和公式,并得到了排叉链环的行列式.本文将利用图论方法给出排叉链环行列式公式的一个简单证明,并证明对任意非负整数k,都有无穷多个行列式等于k的链环.Dasbach et al.offer an alternating sum formula for determinant of links and obtained the determinant for pretzel links.Here we present a simple proof for the ...
戈鋆
core
Advanced determinant calculus: A complement
, 2005 This is a complement to my previous article “Advanced Determinant Calculus” [C. Krattenthaler, Advanced determinant calculus, Séminaire Lotharingien Combin. 42 (1999) (“The Andrews Festschrift”), Article B42q, 67 pp.].
C. Krattenthaler, Krattenthaler, C.
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FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
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Computing Dimensionally Parametrized Determinant Formulas
, 1998 We are interested in dimensionally parametrized determinant formulas for specially structured matrices. Applications of this question occur for example in the study of arbitrary dimensional geometric predicates.
Mark Ziegelmann
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
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