Results 121 to 130 of about 733,924 (247)

Determinants of untimely receipt and non-receipt of routine childhood immunisation in Ebonyi state based on the Adapted Omale INDEPT FORCIS Framework and recommendations for policy and practice: a qualitative study. [PDF]

BMJ Open
Omale UI, Iwegbulam CC, Ekwuazi LC, Amuzie CI, Ikegwuonu CO, Nkwo GE, Ewah RL.   +6 more
europepmc   +1 more source

Self determination [PDF]

British Dental Journal, 2014
openaire   +2 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Examining the underreporting of social determinants of health in randomized controlled trials published in spine journals. [PDF]

Arch Orthop Trauma Surg
Megafu MN, Ayers JT, Evans LC, Newell SA, Uwefoh M, Guerrero OD, Hecht AC, Lin J, Parisien RL, Investigation Performed by the Scientific Collaborative for Orthopaedic Research and Education (SCORE) Group.   +9 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Social determinants of oral health among adults in Saudi Arabia: a narrative review. [PDF]

Saudi Dent J
Alsaif MI.
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

The development of the EUropean Physical Activity Determinants framework for Adolescents (EU-PAD-A): a mixed-methods concept mapping study within the DE-PASS COST action. [PDF]

Int J Behav Nutr Phys Act
Fusco A, Cortis C, Mork PJ, Conte D, Di Rocco F, Festino E, Izzicupo P, Orrù S, Nordstoga AL, Papale O, De Maio M, Presta V, Rocliffe P, Capranica L, MacDonncha C, Condello G.   +15 more
europepmc   +1 more source

Determinate Mutation [PDF]

Science, 1905
openaire   +2 more sources

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source