Results 161 to 170 of about 4,097,781 (367)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Towards a Neural Conversation Model With Diversity Net Using Determinantal Point Processes
, 2018 Yiping Song +5 more
openalex +2 more sources
The Commercial Determinants of Health
Revue d'épidémiologie et de santé publique, 2023 Who Director-General, Margaret Chan
semanticscholar +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The Determinants of Capital Structure Choice
, 1988 S. Titman, R. Wessels
semanticscholar +1 more source
MicroRNA targeting specificity in mammals: determinants beyond seed pairing.
Molecules and Cells, 2007 Andrew Grimson +5 more
semanticscholar +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Promoting the propensity for blood donation through the understanding of its determinants. [PDF]
, 2021 Roberta Guglielmetti Mugion +3 more
openalex +1 more source
Understanding Earnings Quality: A Review of the Proxies, Their Determinants and Their Consequences
, 2010 Patricia M. Dechow +2 more
semanticscholar +1 more source